Breast Cancer Research and Treatment

, Volume 91, Issue 3, pp 279–281

The benefit of participating to clinical research

  • N. Hébert-Croteau
  • J. Brisson
  • J. Lemaire
  • J. Latreille
Brief communication

DOI: 10.1007/s10549-005-0320-0

Cite this article as:
Hébert-Croteau, N., Brisson, J., Lemaire, J. et al. Breast Cancer Res Treat (2005) 91: 279. doi:10.1007/s10549-005-0320-0

Summary

We assessed the impact of participating to clinical research among 1727 women with localized breast cancer. Using as referent individuals not treated according to guidelines for systemic therapy, the adjusted hazard ratio of death was 0.70 (95% confidence interval (CI): 0.54,0.90, p-value: 0.006) in those treated according to current guidelines and 0.45 (95% CI: 0.27,0.73, p-value: 0.001) in participants to research. Participation to clinical trials results in a substantial gain in survival.

Keywords

breast neoplasm clinical trials outcomes research survival 

Copyright information

© Springer 2005

Authors and Affiliations

  • N. Hébert-Croteau
    • 1
    • 2
  • J. Brisson
    • 1
    • 3
  • J. Lemaire
    • 4
  • J. Latreille
    • 2
  1. 1.Direction des Systèmes de Soins et ServicesInstitut National de Santé Publique du QuébecQcCanada
  2. 2.Programme d’OncologieHôpital Charles LeMoyneGreenfield ParkCanada
  3. 3.Unité de Recherche en Santé des PopulationsHôpital du Saint-SacrementQuébecCanada
  4. 4.Département des Sciences Infirmières, Faculté de MédecineUniversité de SherbrookeCanada

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