Breast Cancer Research and Treatment

, Volume 89, Issue 2, pp 145–147 | Cite as

Breast hamartoma: a case report

  • Giovanna Gatti
  • Giovanni Mazzarol
  • Serife Simsek
  • Giuseppe Viale


Breast hamartoma is an uncommon benign lesion, composed of varying amounts of fatty, fibrous and glandular elements. It can present as a breast mass and therefore additional care needs to be taken to rule it out in the differential diagnosis of breast carcinoma. We report a case of a breast hamartoma treated at the European Institute of Oncology.


breast hamartoma case report surgery 


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  1. Baron, M, Ladonne, JM, Gravier, A, Picquenot, JM, Berry, M 2003Invasive lobular carcinoma in a breast hamartomaBreast J9246248CrossRefPubMedGoogle Scholar
  2. Ravakhah, K, Javadi, N, Simms, R 2001Hamartoma of the breast in a man: a case reportBreast J7266268CrossRefPubMedGoogle Scholar
  3. Arrigoni, MG, Dockerty, MB, Judd, ES 1971The identification and treatment of mammary hamartomaSurg Gynecol Obstet133577582PubMedGoogle Scholar
  4. Park, SY, Oh, KK, Kim, EK, Son, EJ, Chung, WH 2003Sonographic findings of breast hamartoma: emphasis on compressibilityYonsei Med J44847854PubMedGoogle Scholar
  5. Eng, C 2003PTEN: one gene, many syndromesHum Mutat22183198PubMedGoogle Scholar
  6. Zhou, XP, Waite, KA, Pilarski, R, Hampel, H, Fernandez, MJ, Bos, C 2003Germline PTEN promoter mutations and deletions in Cowden/Bannayan-Riley-Ruvalcaba syndrome result in aberrant PTEN protein and dysregulation of the phosphoinositol-3-kinase/Akt pathwayAm J Hum Genet73404411PubMedGoogle Scholar
  7. Reifenberger, J, Rauch, L, Beckmann, MW, Megahed, M, Ruzicka, T, Reifenberger, G 2003Cowden’s disease: clinical and molecular genetic findings in a patient with a novel PTEN germline mutationBr J Dermatol14810401046CrossRefPubMedGoogle Scholar
  8. Fistarol, SK, Anliker, MD, Itin, PH 2002Cowden disease or multiple hamartoma syndrome–cutaneous clue to internal malignancyEur J Dermatol12411421PubMedGoogle Scholar
  9. Schrager, CA, Schneider, D, Gruener, AC, Tsou, HC, Peacocke, M 1998Similarities of cutaneous and breast pathology in Cowden’s diseaseExp Dermatol7380390PubMedGoogle Scholar
  10. Schweitzer, S, Hogge, JP, Grimes, M, Bear, HD, Paredes, ES 1999Cowden disease: a cutaneous marker for increased risk of breast cancerAm J Roentgenol172349351Google Scholar
  11. Schrager, CA, Schneider, D, Gruener, AC, Tsou, HC, Peacocke, M 1998Clinical and pathological features of breast disease in Cowden’s syndrome. An underrecognized syndrome with an increased risk of breast cancerHum Pathol294753CrossRefPubMedGoogle Scholar
  12. Gomez-Aracil, V, Mayayo, E, Azua, J, Mayayo, R, Azua-Romeo, J, Arraiza, A 2003Fine needle aspiration cytology of mammary hamartoma: a review of nine cases with histological correlationCytopathology14195200CrossRefPubMedGoogle Scholar
  13. Herbert, M, Schvimer, M, Zehavi, S, Mendlovic, S, Karni, T, Pappo, I, Sandbank, J 2003Breast hamartoma: fine-needle aspiration cytologic findingCancer99255258CrossRefPubMedGoogle Scholar

Copyright information

© Springer 2005

Authors and Affiliations

  • Giovanna Gatti
    • 1
    • 2
    • 3
  • Giovanni Mazzarol
    • 4
  • Serife Simsek
    • 1
  • Giuseppe Viale
    • 4
    • 5
  1. 1.Division of Breast SurgeryEuropean Institute of OncologyMilanItaly
  2. 2.Scientific Director’s OfficeEuropean Institute of OncologyMilan
  3. 3.Postgraduate School of General Surgery University of PerugiaMilan
  4. 4.Division of PathologyEuropean Institute of OncologyMilan
  5. 5.University of MilanItaly

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