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The Role of the Temporoparietal Junction in Self-Other Distinction

  • François Quesque
  • Marcel BrassEmail author
Review
  • 92 Downloads

Abstract

Being able to discriminate between what originates from ourselves and what originates from others is critical for efficient interactions with our social environment. However, it remains an open question whether self-other distinction is a domain-general mechanism that is involved in various social-cognitive functions or whether specific ‘self-other distinction mechanisms’ exist for each of these functions. On the neural level, there is evidence that self-other distinction is related to a specific brain region at the border of the superior temporal and inferior parietal cortex, the temporoparietal junction (TPJ). Demonstrating that the TPJ plays a role in social processes that require self-other distinction would support the idea of a domain-general mechanism of self-other distinction. In the present paper, we review evidence coming from clinical observations, neuroimaging experiments and a meta-analysis indicating the involvement of the TPJ in various cognitive operations requiring self-other distinction. At the perceptual level, we discuss the human ability to identify one’s own body and to distinguish it from others. At the action level, we review research on the human ability to experience agency and the control of imitative response tendencies. Finally, at the mental-state level, we discuss the ability to attribute mental states to others. Based on this integrative review, we suggest that the TPJ, and in particular its dorsal part, supports a domain general ability to enhance task-relevant representations when self-related and other-related representations are in conflict. Finally, this conception allows us to propose a unifying architecture for the emergence of numerous socio-cognitive abilities.

Keywords

Temporoparietal junction TPJ Self-other distinction Theory of mind Agency 

Notes

References

  1. Abraham A, Schubotz RI, von Cramon DY (2008) Thinking about the future versus the past in personal and non-personal contexts. Brain Res 1233:106–119CrossRefPubMedGoogle Scholar
  2. Aichhorn M, Perner J, Kronbichler M, Staffen W, Ladurner G (2006) Do visual perspective tasks need theory of mind? Neuroimage 30(3):1059–1068CrossRefPubMedGoogle Scholar
  3. Apperly IA, Butterfill SA (2009) Do humans have two systems to track beliefs and belief-like states? Psychol Rev 116(4):953–970CrossRefPubMedGoogle Scholar
  4. Arora A, Schurz M, Perner J (2017) Systematic comparison of brain imaging meta-analyses of ToM with vPT. BioMed Research InternationalGoogle Scholar
  5. Bardi L, Brass M (2016) The control of shared representations and social cognition. Shared representations. Cambridge University Press, Cambridge, pp 151–170Google Scholar
  6. Bardi L, Gheza D, Brass M (2017) TPJ-M1 interaction in the control of shared representations: new insights from tDCS and TMS combined. NeuroImage 146:734–740CrossRefPubMedGoogle Scholar
  7. Berlucchi G, Aglioti S (1997) The body in the brain: neural bases of corporeal awareness. Trends Neurosci 20(12):560–564CrossRefPubMedGoogle Scholar
  8. Blakemore SJ, Smith J, Steel R, Johnstone EC, Frith CD (2000) The perception of self-produced sensory stimuli in patients with auditory hallucinations and passivity experiences: evidence for a breakdown in self-monitoring. Psychol Med 30(5):1131–1139CrossRefPubMedGoogle Scholar
  9. Blanke O, Arzy S (2005) The out-of-body experience: disturbed self-processing at the temporo-parietal junction. Neuroscientist 11(1):16–24CrossRefPubMedGoogle Scholar
  10. Blanke O, Ortigue S, Landis T, Seeck M (2002) Neuropsychology: stimulating illusory own-body perceptions. Nature 419(6904):269CrossRefPubMedGoogle Scholar
  11. Boccadoro S, Cracco E, Hudson A, Bardi L, Nijhof A, Wiersema JR, Brass M, Mueller S (2019) Defining the neural correlates of spontaneous theory of mind (ToM): an fMRI mega-analytic investigation. bioRxiv, 560953Google Scholar
  12. Botvinick M, Cohen J (1998) Rubber hands ‘feel’touch that eyes see. Nature 391(6669):756CrossRefPubMedGoogle Scholar
  13. Brass M, Heyes C (2005) Imitation: is cognitive neuroscience solving the correspondence problem? Trends Cognit Sci 9(10):489–495CrossRefGoogle Scholar
  14. Brass M, Bekkering H, Wohlschläger A, Prinz W (2000) Compatibility between observed and executed finger movements: comparing symbolic, spatial, and imitative cues. Brain Cognit 44:124–143CrossRefGoogle Scholar
  15. Brass M, Zysset S, von Cramon DY (2001) The inhibition of imitative response tendencies. Neuroimage 14(6):1416–1423CrossRefPubMedGoogle Scholar
  16. Brass M, Derrfuss J, von Cramon DY (2005) The inhibition of imitative and overlearned responses: a functional double dissociation. Neuropsychologia 43(1):89–98CrossRefPubMedGoogle Scholar
  17. Brass M, Ruby P, Spengler S (2009) Inhibition of imitative behaviour and social cognition. Philos Trans R Soc B 364(1528):2359–2367CrossRefGoogle Scholar
  18. Braun N, Debener S, Spychala N, Bongartz E, Sorös P, Müller HHO, Philipsen A (2018) The senses of agency and ownership: a review. Front Psychol 9:535CrossRefPubMedPubMedCentralGoogle Scholar
  19. Brozzoli C, Gentile G, Ehrsson HH (2012) That’s near my hand! Parietal and premotor coding of hand-centered space contributes to localization and self-attribution of the hand. J Neurosci 32(42):14573–14582CrossRefPubMedPubMedCentralGoogle Scholar
  20. Brugger P, Lenggenhager B (2014) The bodily self and its disorders: neurological, psychological and social aspects. Curr Opin Neurol 27(6):644–652CrossRefPubMedGoogle Scholar
  21. Buehner MJ (2012) Understanding the past, predicting the future: causation, not intentional action, is the root of temporal binding. Psychol Sci 23(12):1490–1497CrossRefPubMedGoogle Scholar
  22. Bukowski H, Lamm C (2017) Temporoparietal junction. In: Zeigler-Hill V, Shackelford TK (eds) Encyclopedia of personality and individual differences. Springer, New York, pp 1–5Google Scholar
  23. Bzdok D, Langner R, Schilbach L, Jakobs O, Roski C, Caspers S, Laird AR, Fox PT, Zilles K, Eickhoff SB (2013) Characterization of the temporo-parietal junction by combining data-driven parcellation, complementary connectivity analyses, and functional decoding. NeuroImage 81:381–392CrossRefPubMedPubMedCentralGoogle Scholar
  24. Cabeza R, Ciaramelli E, Moscovitch M (2012) Cognitive contributions of the ventral parietal cortex: an integrative theoretical account. Trends Cognit Sci 16(6):338–352CrossRefGoogle Scholar
  25. Carruthers P (2015) Mindreading in adults: evaluating two-systems views. Synthese 194:1–16Google Scholar
  26. Carter RM, Huettel SA (2013) A nexus model of the temporal–parietal junction. Trends Cognit Sci 17(7):328–336CrossRefGoogle Scholar
  27. Chambon V, Wenke D, Fleming SM, Prinz W, Haggard P (2012) An online neural substrate for sense of agency. Cereb Cortex 23(5):1031–1037CrossRefPubMedGoogle Scholar
  28. Corbetta M, Shulman GL (2002) Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 3(3):201CrossRefPubMedPubMedCentralGoogle Scholar
  29. Corbetta M, Patel G, Shulman GL (2008) The reorienting system of the human brain: from environment to theory of mind. Neuron 58(3):306–324CrossRefPubMedPubMedCentralGoogle Scholar
  30. Daprati E, Franck N, Georgieff N, Proust J, Pacherie E, Dalery J, Jeannerod M (1997) Looking for the agent: an investigation into consciousness of action and self-consciousness in schizophrenic patients. Cognition 65(1):71–86CrossRefPubMedGoogle Scholar
  31. Darda KM, Ramsey R (2019) The inhibition of automatic imitation: a meta-analysis and synthesis of fMRI studies. NeuroImage 197:320–329CrossRefPubMedGoogle Scholar
  32. David N, Newen A, Vogeley K (2008) The “sense of agency” and its underlying cognitive and neural mechanisms. Conscious Cognit 17(2):523–534CrossRefGoogle Scholar
  33. Decety J, Lamm C (2007) The role of the right temporoparietal junction in social interaction: how low-level computational processes contribute to meta-cognition. Neuroscientist 13(6):580–593CrossRefPubMedPubMedCentralGoogle Scholar
  34. Devinsky O (2000) Right cerebral hemisphere dominance for a sense of corporeal and emotional self. Epilepsy Behav 1:60–73CrossRefGoogle Scholar
  35. Dewey JA, Knoblich G (2014) Do implicit and explicit measures of the sense of agency measure the same thing? PLoS ONE 9(10):e110118CrossRefPubMedPubMedCentralGoogle Scholar
  36. Ehrsson HH, Spence C, Passingham RE (2004) That’s my hand! Activity in premotor cortex reflects feeling of ownership of a limb. Science 305(5685):875–877CrossRefGoogle Scholar
  37. Ehrsson HH, Wiech K, Weiskopf N, Dolan RJ, Passingham RE (2007) Threatening a rubber hand that you feel is yours elicits a cortical anxiety response. Proc Natl Acad Sci 104(23):9828–9833CrossRefPubMedGoogle Scholar
  38. Farrer C, Frith CD (2002) Experiencing oneself vs another person as being the cause of an action: the neural correlates of the experience of agency. Neuroimage 15(3):596–603CrossRefPubMedGoogle Scholar
  39. Farrer C, Franck N, Georgieff N, Frith CD, Decety J, Jeannerod M (2003) Modulating the experience of agency: a positron emission tomography study. Neuroimage 18(2):324–333CrossRefPubMedGoogle Scholar
  40. Gallagher S (2000) Philosophical conceptions of the self: implications for cognitive science. Trends Cognit Sci 4(1):14–21CrossRefGoogle Scholar
  41. Gallagher HL, Happé F, Brunswick N, Fletcher PC, Frith U, Frith CD (2000) Reading the mind in cartoons and stories: an fMRI study of ‘theory of mind’ in verbal and nonverbal tasks. Neuropsychologia 38(1):11–21CrossRefPubMedGoogle Scholar
  42. Gallotti M, Frith CD (2013) Social cognition in the we-mode. Trends Cognit Sci 17(4):160–165CrossRefGoogle Scholar
  43. Gandola M, Invernizzi P, Sedda A, Ferrè ER, Sterzi R, Sberna M, Paulesu E, Bottini G (2012) An anatomical account of somatoparaphrenia. Cortex 48(9):1165–1178CrossRefPubMedGoogle Scholar
  44. Gentile G, Guterstam A, Brozzoli C, Ehrsson HH (2013) Disintegration of multisensory signals from the real hand reduces default limb self-attribution: an fMRI study. J Neurosci 33(33):13350–13366CrossRefPubMedPubMedCentralGoogle Scholar
  45. Gillihan SJ, Farah MJ (2005) Is self special? A critical review of evidence from experimental psychology and cognitive neuroscience. Psychol Bull 131(1):76CrossRefPubMedGoogle Scholar
  46. Haggard P (2017) Sense of agency in the human brain. Nat Rev Neurosci 18(4):196CrossRefPubMedGoogle Scholar
  47. Happé F, Cook JL, Bird G (2017) The structure of social cognition: in (ter) dependence of sociocognitive processes. Annu Rev Psychol 68:243–267CrossRefPubMedGoogle Scholar
  48. Hecht EE, Patterson R, Barbey AK (2012) What can other animals tell us about human social cognition? An evolutionary perspective on reflexive and reflective processing. Front Hum Neurosci 6:224CrossRefPubMedPubMedCentralGoogle Scholar
  49. Heyes C (2014) Submentalizing: i’ m not really reading your mind. Psychol Sci 9:121–143Google Scholar
  50. Heyes C (2018) Précis of cognitive gadgets: The cultural evolution of thinking. Behav Brain Sci 42:1–57Google Scholar
  51. Hogeveen J, Obhi SS, Banissy MJ, Santiesteban I, Press C, Catmur C, Bird G (2014) Task-dependent and distinct roles of the temporoparietal junction and inferior frontal cortex in the control of imitation. Soc Cognit Affect Neurosci 10(7):1003–1009CrossRefGoogle Scholar
  52. Jeannerod M (2003) The mechanism of self-recognition in humans. Behav Brain Res 142(1–2):1–15CrossRefPubMedGoogle Scholar
  53. Just MA, Carpenter PA, Keller TA, Eddy WF, Thulborn KR (1996) Brain activation modulated by sentence comprehension. Science 274(5284):114–116CrossRefPubMedGoogle Scholar
  54. Keenan JP, Freund S, Hamilton RH, Ganis G, Pascual-Leone A (2000) Hand response differences in a self-face identification task. Neuropsychologia 38:1047–1053CrossRefPubMedGoogle Scholar
  55. Krall SC, Rottschy C, Oberwelland E, Bzdok D, Fox PT, Eickhoff SB, Fink GR, Konrad K (2015) The role of the right temporoparietal junction in attention and social interaction as revealed by ALE meta-analysis. Brain Struct Funct 220(2):587–604CrossRefPubMedGoogle Scholar
  56. Kühn S, Brass M, Haggard P (2013) Feeling in control: neural correlates of experience of agency. Cortex 49(7):1935–1942CrossRefPubMedGoogle Scholar
  57. Lamm C, Bukowski H, Silani G (2016) From shared to distinct self–other representations in empathy: evidence from neurotypical function and socio-cognitive disorders. Philos Trans R Soc B 371(1686):20150083CrossRefGoogle Scholar
  58. Lombardo MV, Chakrabarti B, Bullmore ET, Wheelwright SJ, Sadek SA, Suckling J, Baron-Cohen S, MRC Aims Consortium, Baron-Cohen S (2010) Shared neural circuits for mentalizing about the self and others. J Cognit Neurosci 22(7):1623–1635CrossRefGoogle Scholar
  59. Mar RA (2011) The neural bases of social cognition and story comprehension. Annu Rev Psychol 62:103–134CrossRefPubMedGoogle Scholar
  60. Mars RB, Sallet J, Schüffelgen U, Jbabdi S, Toni I, Rushworth MF (2012) Connectivity-based subdivisions of the human right “temporoparietal junction area”: evidence for different areas participating in different cortical networks. Cereb Cortex 22(8):1894–1903CrossRefPubMedGoogle Scholar
  61. Marsh LE, Bird G, Catmur C (2016) The imitation game: effects of social cues on ‘imitation’are domain-general in nature. NeuroImage 139:368–375CrossRefPubMedGoogle Scholar
  62. Mitchell JP (2007) Activity in right temporo-parietal junction is not selective for theory-of-mind. Cereb Cortex 18(2):262–271CrossRefPubMedGoogle Scholar
  63. Neisser U (1995) Criterion for an ecological self. In: Rochat P (ed) The self in infancy: theory and research. Elsevier, Amsterdam, pp 17–34CrossRefGoogle Scholar
  64. Nieuwenhuys R, Voogd J, Van Huijzen C (2007) The human central nervous system: a synopsis and atlas. Springer Science & Business Media, BerlinGoogle Scholar
  65. Petkova VI, Ehrsson HH (2008) If I were you: perceptual illusion of body swapping. PLoS ONE 3(12):e3832CrossRefPubMedPubMedCentralGoogle Scholar
  66. Piaget J, Inhelder B (1948) The child’s conception of space. Routledge and Kegan Paul, LondonGoogle Scholar
  67. Poldrack RA (2006) Can cognitive processes be inferred from neuroimaging data? Trends Cognit Sci 10(2):59–63CrossRefGoogle Scholar
  68. Poldrack RA (2011) Inferring mental states from neuroimaging data: from reverse inference to large-scale decoding. Neuron 72(5):692–697CrossRefPubMedPubMedCentralGoogle Scholar
  69. Premack D, Woodruff G (1978) Does the chimpanzee have a theory of mind? Behav Brain Sci 1:515–526CrossRefGoogle Scholar
  70. Pulvermüller F (2005) Brain mechanisms linking language and action. Nat Rev Neurosci 6(7):576CrossRefPubMedGoogle Scholar
  71. Quesque F, Chabanat E, Rossetti Y (2018) Taking the point of view of the blind: spontaneous level-2 perspective-taking in irrelevant conditions. J Exp Soc Psychol 79:356–364CrossRefGoogle Scholar
  72. Rogers C (1951) Client-centred therapy. Houghton-Mifflin, BostonGoogle Scholar
  73. Quesque F, Rossetti, Y (in press) What do theory of mind tasks actually measure? Theory and practice. Perspect Psychol SciGoogle Scholar
  74. Santiesteban I, Banissy MJ, Catmur C, Bird G (2015) Functional lateralization of temporoparietal junction–imitation inhibition, visual perspective-taking and theory of mind. Eur J Neurosci 42(8):2527–2533CrossRefPubMedGoogle Scholar
  75. Saxe R, Kanwisher N (2003) People thinking about thinking people: the role of the temporo-parietal junction in “theory of mind”. Neuroimage 19(4):1835–1842CrossRefPubMedGoogle Scholar
  76. Saxe R, Wexler A (2005) Making sense of another mind: the role of the right temporo-parietal junction. Neuropsychologia 43:1391–1399CrossRefPubMedGoogle Scholar
  77. Schurz M, Aichhorn M, Martin A, Perner J (2013) Common brain areas engaged in false belief reasoning and visual perspective taking: a meta-analysis of functional brain imaging studies. Front Hum Neurosci 7:712CrossRefPubMedPubMedCentralGoogle Scholar
  78. Schurz M, Kronbichler M, Weissengruber S, Surtees A, Samson D, Perner J (2015) Clarifying the role of theory of mind areas during visual perspective taking: issues of spontaneity and domain-specificity. NeuroImage 117:386–396CrossRefPubMedGoogle Scholar
  79. Serences JT, Shomstein S, Leber AB, Golay X, Egeth HE, Yantis S (2005) Coordination of voluntary and stimulus-driven attentional control in human cortex. Psychol Sci 16(2):114–122CrossRefPubMedGoogle Scholar
  80. Sierra M (2009) Depersonalization: a new look at a neglected syndrome. Cambridge University Press, CambridgeCrossRefGoogle Scholar
  81. Sierra M, Berrios GE (1998) Depersonalization: neurobiological perspectives. Biol Psychiat 44(9):898–908CrossRefPubMedGoogle Scholar
  82. Silani G, Lamm C, Ruff CC, Singer T (2013) Right supramarginal gyrus is crucial to overcome emotional egocentricity bias in social judgments. J Neurosci 33(39):15466–15476CrossRefPubMedPubMedCentralGoogle Scholar
  83. Soutschek A, Ruff CC, Strombach T, Kalenscher T, Tobler PN (2016) Brain stimulation reveals crucial role of overcoming self-centeredness in self-control. Sci Adv 2(10):e1600992CrossRefPubMedPubMedCentralGoogle Scholar
  84. Sowden S, Catmur C (2015) The role of the right temporoparietal junction in the control of imitation. Cereb Cortex 25(4):1107–1113CrossRefPubMedGoogle Scholar
  85. Spengler S, von Cramon DY, Brass M (2009) Was it me or was it you? How the sense of agency originates from ideomotor learning revealed by fMRI. Neuroimage 46(1):290–298CrossRefPubMedGoogle Scholar
  86. Sperduti M, Delaveau P, Fossati P, Nadel J (2011) Different brain structures related to self-and external-agency attribution: a brief review and meta-analysis. Brain Struct Funct 216(2):151–157CrossRefPubMedGoogle Scholar
  87. Tomova L, von Dawans B, Heinrichs M, Silani G, Lamm C (2014) Is stress affecting our ability to tune into others? Evidence for gender differences in the effects of stress on self-other distinction. Psychoneuroendocrinology 43:95–104CrossRefPubMedGoogle Scholar
  88. Tsakiris M, Haggard P (2005) The rubber hand illusion revisited: visuotactile integration and self-attribution. J Exp Psychol Hum Percept Perform 31(1):80CrossRefPubMedGoogle Scholar
  89. Uddin LQ (2011) The self in autism: an emerging view from neuroimaging. Neurocase 17(3):201–208CrossRefPubMedPubMedCentralGoogle Scholar
  90. Uddin LQ, Molnar-Szakacs I, Zaidel E, Iacoboni M (2006) rTMS to the right inferior parietal lobule disrupts self-other discrimination. Soc Cognit Affect Neurosci 1:65–71CrossRefGoogle Scholar
  91. Van Ackeren MJ, Casasanto D, Bekkering H, Hagoort P, Rueschemeyer SA (2012) Pragmatics in action: indirect requests engage theory of mind areas and the cortical motor network. J Cognit Neurosci 24(11):2237–2247CrossRefGoogle Scholar
  92. Van Overwalle F (2009) Social cognition and the brain: a meta-analysis. Hum Brain Mapp 30(3):829–858CrossRefPubMedGoogle Scholar
  93. Vogeley K, Fink GR (2003) Neural correlates of the first-person perspective. Trends Cognit Neurosci 7:38–42CrossRefGoogle Scholar
  94. Vogeley K, Bussfeld P, Newen A, Herrmann S, Happé F, Falkai P, Maier W, Shah NJ, Fink GR, Zilles K (2001) Mind reading: neural mechanisms of theory of mind and self-perspective. Neuroimage 14(1):170–181CrossRefPubMedGoogle Scholar
  95. Wegner DM, Wheatley T (1999) Apparent mental causation: sources of the experience of will. Am Psychol 54(7):480CrossRefPubMedGoogle Scholar
  96. Wimmer H, Perner J (1983) Beliefs about beliefs: representation and constraining function of wrong beliefs in young children’s understanding of deception. Cognition 13:103–128CrossRefPubMedGoogle Scholar
  97. Yarkoni T, Poldrack RA, Nichols TE, Van Essen DC, Wager TD (2011) Large-scale automated synthesis of human functional neuroimaging data. Nat Methods 8(8):665CrossRefPubMedPubMedCentralGoogle Scholar
  98. Young L, Camprodon JA, Hauser M, Pascual-Leone A, Saxe R (2010a) Disruption of the right temporoparietal junction with transcranial magnetic stimulation reduces the role of beliefs in moral judgments. Proc Natl Acad Sci 107(15):6753–6758CrossRefPubMedGoogle Scholar
  99. Young L, Dodell-Feder D, Saxe R (2010b) What gets the attention of the temporo-parietal junction? An fMRI investigation of attention and theory of mind. Neuropsychologia 48:2658–2664CrossRefPubMedGoogle Scholar
  100. Zaitchik D, Walker C, Miller S, LaViolette P, Feczko E, Dickerson BC (2010) Mental state attribution and the temporoparietal junction: an fMRI study comparing belief, emotion, and perception. Neuropsychologia 48(9):2528–2536CrossRefPubMedPubMedCentralGoogle Scholar

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Authors and Affiliations

  1. 1.Department of Experimental PsychologyGhent UniversityGhentBelgium
  2. 2.CMRRLilleFrance

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