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Journal of Inherited Metabolic Disease

, Volume 29, Issue 6, pp 763–763 | Cite as

Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis

  • M. Cailliez
  • F. Garaix
  • C. Rousset-Rouvière
  • D. Bruno
  • I. Kone-Paut
  • J. Sarles
  • B. Chabrol
  • M. Tsimaratos
Short Report

Summary

Hyper-IgD and periodic fever syndrome (HIDS) is a hereditary autoinflammatory syndrome, characterized by recurrent inflammatory attacks. Treatment of HIDS is difficult. Recently, the IL-1ra analogue anakinra was reported to be successful in aborting the IgD inflammatory attacks in a vaccination model. We report a clinical case of spectacular reduction of febrile attacks in a severe HIDS patient.

Keywords

Public Health Internal Medicine Electronic Supplementary Material Metabolic Disease Clinical Case 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

10545_2006_ESM_408.pdf (197 kb)
Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis

Copyright information

© SSIEM and Springer 2006

Authors and Affiliations

  • M. Cailliez
    • 1
  • F. Garaix
    • 1
  • C. Rousset-Rouvière
    • 1
  • D. Bruno
    • 1
  • I. Kone-Paut
    • 2
  • J. Sarles
    • 1
  • B. Chabrol
    • 1
  • M. Tsimaratos
    • 1
  1. 1.AP-HM Timone-EnfantsMarseilles Cedex 05France
  2. 2.Department of PediatricsHôpital de Bicetre, Le Kremlin BicetreParisFrance

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