Biomedical Microdevices

, Volume 14, Issue 4, pp 669–677 | Cite as

A high-flux isopore micro-fabricated membrane for effective concentration and recovering of waterborne pathogens

  • Majid Ebrahimi Warkiani
  • Chao-Ping Lou
  • Hao-Bing Liu
  • Hai-Qing GongEmail author


A high-flux metallic micro/nano-filtration membrane has been fabricated and validated for isolation of waterborne pathogens from drinking water. Obtained membrane with smooth surface and perfectly ordered pores was achieved by a high yield and cost effective multilevel lithography and electroplating technique. The micro-fabricated membrane was also strengthened with an integrated back-support, which can withstand a high pressure during filtration. The results of microfiltration tests with model particles revealed the superior performance of the micro-fabricated filter than current commercial filters in sample throughput, recovery ratio, and reusability. This study highlighted the potential application of micro-fabricated filer in rapid filtration and recovery of C. parvum oocysts for downstream analysis.


Micro-fabricated membrane Lithography Fouling Pathogen Microfiltration 



The authors acknowledge the financial support of the Environment & Water Industry Programme Office of Singapore under the project grant MEWR 651/06/170.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Majid Ebrahimi Warkiani
    • 1
  • Chao-Ping Lou
    • 1
  • Hao-Bing Liu
    • 1
  • Hai-Qing Gong
    • 1
    Email author
  1. 1.School of Mechanical and Aerospace EngineeringNanyang Technological UniversitySingaporeSingapore

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