Biochemistry (Moscow)

, Volume 70, Issue 2, pp 154–158 | Cite as

Cardiolipin in energy transducing membranes

  • E. Mileykovskaya
  • M. Zhang
  • W. Dowhan


Cardiolipin is a phospholipid located exclusively in energy transducing membranes such as the bacterial cytoplasmic membrane and the inner membrane of mitochondria. It plays both a structural and a functional role in many multimeric complexes associated with these membranes. The role of cardiolipin in higher order organization of components of the mitochondrial respiratory chain revealed by a combined molecular genetic and biochemical approach is described.

Key words

cardiolipin supercomplex yeast mitochondria 


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Copyright information

© MAIK “Nauka/Interperiodica” 2005

Authors and Affiliations

  1. 1.Department of Biochemistry and Molecular BiologyUniversity of Texas Houston, Medical SchoolHouston sUSA

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