, Volume 22, Issue 4, pp 679–689 | Cite as

The redox hypothesis in siderophore-mediated iron uptake

  • James M. Harrington
  • Alvin L. CrumblissEmail author


The viability of iron(III/II) reduction as the initial step in the in vivo release of iron from its thermodynamically stable siderophore complex is explored.


Iron bioavailability Iron transport Redox potentials Redox kinetics 



We thank the National Science Foundation (CHE 0809466) for their support of our work in this area.


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Copyright information

© Springer Science+Business Media, LLC. 2009

Authors and Affiliations

  1. 1.Department of ChemistryDuke UniversityDurhamUSA

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