Tobacco smoke iron: an initiator/promoter of multiple diseases
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Tobacco smoking enhances risk for a diversity of acute and chronic diseases. Iron is a constant prominent component of mainstream tobacco smoke. The manifold toxic activities of inhaled iron could be responsible for a notable portion of the spectrum of smoking-related diseases.
KeywordsImpaired hearing Infection Iron Neoplasm Osteoporosis Tobacco smoke Vascular disease
Dedicated to Dr. L. S. Wesselius in recognition of his distinguished career in respiratory tract physiology and iron metabolism.
- Basaraba RJ, Bielefeldt-Ohmann H, Eschelbach EK, Tolmay AE, Taraba LC, Shanlay CA et al (2008) Increased expression of host iron-binding proteins precedes iron accumulation and calcification of primary lung lesions in experimental tuberculosis in the guinea pig. Tuberculosis (Edinb) 88:69–79. doi: 10.1016/j.tube.2007.09.002 CrossRefGoogle Scholar
- Edelstein PH (2008) Legionairre’s disease. In: Goldman L, Ausiello D (eds) Cecil medicine, 23rd edn. Saunders Elsevier, Philadelphia, pp 2261–2265Google Scholar
- Mussala-Rauhammae H, Salmela SS, Lepannen A, Pyysalo H (1986) Cigarettes as a source of some trace and heavy metals and pesticides in man. Arch Environ Health 41:49–55Google Scholar
- Viswanathan VK, Cianciotto NP (2001) Role of iron acquisition in Legionella pneumophila virulence. Microbe 67:253–258Google Scholar