Biotechnology Letters

, Volume 40, Issue 9–10, pp 1303–1309 | Cite as

Current state of the art in continuous bioprocessing

  • Mark SchofieldEmail author


There is an upsurge of interest in continuous bioprocessing, but currently continuous downstream bioprocessing has not been implemented to generate clinical material. This review focusses on the current state of the art of continuous downstream processing, highlighting the key advantages over traditional batch manufacturing. This allows the identification of scenarios where continuous downstream processing may be critical for commercial manufacturing success.


Continuous downstream processing Bioprocess intensification Clinical manufacturing 


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Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  1. 1.Pall BiotechWestboroughUSA

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