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Biotechnology Letters

, Volume 39, Issue 5, pp 647–666 | Cite as

Structural and functional characteristics of plant proteinase inhibitor-II (PI-II) family

  • Shazia Rehman
  • Ejaz Aziz
  • Wasim Akhtar
  • Muhammad Ilyas
  • Tariq Mahmood
REVIEW

Abstract

Plant proteinase inhibitor-II (PI-II) proteins are one of the promising defensive proteins that helped the plants to resist against different kinds of unfavorable conditions. Different roles for PI-II have been suggested such as regulation of endogenous proteases, modulation of plant growth and developmental processes and mediating stress responses. The basic knowledge on genetic and molecular diversity of these proteins has provided significant insight into their gene structure and evolutionary relationships in various members of this family. Phylogenetic comparisons of these family genes in different plants suggested that the high rate of retention of gene duplication and inhibitory domain multiplication may have resulted in the expansion and functional diversification of these proteins. Currently, a large number of transgenic plants expressing PI-II genes are being developed for enhancing the defensive capabilities against insects, bacteria and pathogenic fungi. Much emphasis is yet to be given to exploit this ever expanding repertoire of genes for improving abiotic stress resistance in transgenic crops. This review presents an overview about the current knowledge on PI-II family genes, their multifunctional role in plant defense and physiology with their potential applications in biotechnology.

Keywords

Multifunctional role Proteinase inhibitor-II (PI-II) proteins Stress responses Transgenic plants 

Notes

Acknowledgement

This work was financially supported by the Higher Education Commission, Islamabad, Pakistan.

Compliance with ethical standards

Conflict of interest

The authors declared that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media Dordrecht 2017

Authors and Affiliations

  • Shazia Rehman
    • 1
  • Ejaz Aziz
    • 1
  • Wasim Akhtar
    • 2
  • Muhammad Ilyas
    • 1
  • Tariq Mahmood
    • 1
  1. 1.Department of Plant SciencesQuaid-i-Azam UniversityIslamabadPakistan
  2. 2.Department of BiotechnologyUniversity of Azad Jammu and KashmirMuzaffarabadPakistan

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