Biotechnology Letters

, Volume 34, Issue 8, pp 1415–1434 | Cite as

Butanol production from lignocellulosics

  • German Jurgens
  • Shrikant Survase
  • Oxana Berezina
  • Evangelos Sklavounos
  • Juha Linnekoski
  • Antti Kurkijärvi
  • Minna Väkevä
  • Adriaan van Heiningen
  • Granström Tom Email author


Clostridium spp. produce n-butanol in the acetone/butanol/ethanol process. For sustainable industrial scale butanol production, a number of obstacles need to be addressed including choice of feedstock, the low product yield, toxicity to production strain, multiple-end products and downstream processing of alcohol mixtures. This review describes the use of lignocellulosic feedstocks, bioprocess and metabolic engineering, downstream processing and catalytic refining of n-butanol.


Acetone/butanol/ethanol fermentation Butanol Chemical catalysis Downstream processing Lignocellulosics 



Authors would like to acknowledge and thank Professor Matti Leisola (Department of Biotechnology and Chemical Technology, Aalto University, Finland) for the valuable comments, suggestions and corrections of the manuscript.


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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • German Jurgens
    • 1
  • Shrikant Survase
    • 1
  • Oxana Berezina
    • 2
  • Evangelos Sklavounos
    • 3
  • Juha Linnekoski
    • 1
  • Antti Kurkijärvi
    • 1
  • Minna Väkevä
    • 1
  • Adriaan van Heiningen
    • 3
    • 4
  • Granström Tom 
    • 1
    Email author
  1. 1.Department of Biotechnology and Chemical TechnologyAalto UniversityEspooFinland
  2. 2.State Research Institute of Genetics and Selection of Industrial MicroorganismsMoscowRussian Federation
  3. 3.Department of Forest Products ChemistryAalto UniversityEspooFinland
  4. 4.Department of Chemical and Biological EngineeringUniversity of MaineOronoUSA

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