Biotechnology Letters

, Volume 31, Issue 3, pp 377–380 | Cite as

High-yield production of erythritol from raw glycerol in fed-batch cultures of Yarrowia lipolytica

  • Waldemar Rymowicz
  • Anita Rywińska
  • Marta Marcinkiewicz
Original Research Paper


An acetate-negative mutant of Yarrowia lipolytica Wratislavia K1 was selected that, when grown with 300 g raw glycerol l−1 at pH 3, produced 170 g erythritol l−1 after 7 days, corresponding to a 56% yield and a productivity of 1 g l−1 h−1. The Wratislavia K1 strain did not produce citric acid.


Erythritol production Fed-batch Raw glycerol Yarrowia lipolytica 



This work was financed by the Ministry of Sciences and Higher Education of Poland under Project No. 2P06T 044 30.


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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • Waldemar Rymowicz
    • 1
  • Anita Rywińska
    • 1
  • Marta Marcinkiewicz
    • 1
  1. 1.Department of Biotechnology and Food MicrobiologyWroclaw University of Environmental and Life SciencesWroclawPoland

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