High-yield production of erythritol from raw glycerol in fed-batch cultures of Yarrowia lipolytica
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An acetate-negative mutant of Yarrowia lipolytica Wratislavia K1 was selected that, when grown with 300 g raw glycerol l−1 at pH 3, produced 170 g erythritol l−1 after 7 days, corresponding to a 56% yield and a productivity of 1 g l−1 h−1. The Wratislavia K1 strain did not produce citric acid.
KeywordsErythritol production Fed-batch Raw glycerol Yarrowia lipolytica
This work was financed by the Ministry of Sciences and Higher Education of Poland under Project No. 2P06T 044 30.
- Papanikolaou S, Fakas S, Fick M, Chevalot I, Galiotou-Panayotou M (2008) Biotechnological valorisation of raw glycerol discharged after bio-diesel (fatty acid methyl esters) manufacturing process: Production of 1, 3-propanediol, citric acid and single cell oil. Biomass Bioeng 32:60–71CrossRefGoogle Scholar
- Veigada-Cunha M, Firme P, San-Romao MV, Santos H (1992) Application of 13C nuclear magnetic resonance to elucidate the unexpected biosynthesis of erythritol by Leuconostoc oenos. Appl Environ Microbiol 58:2271–2279Google Scholar