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Biotechnological challenges of phage therapy

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Abstract

The challenges for successful launching of a profitable phage therapeutic product include intellectual property rights, safety issues, reproducibility, stability and robustness of the product. A successful and marketable product would be a highly purified bacteriophage preparation containing one or several fully characterized phages, accompanied by optimized methods of administration and backed up by properly controlled efficacy and safety studies.

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Authors and Affiliations

  1. Department of Bacteriology and Immunology, Haartman Institute, University of Helsinki, P. O. Box 21, 00014, Helsinki, Finland

    Mikael Skurnik

  2. Institute of Biotechnology, University of Helsinki, Helsinki, Finland

    Maria Pajunen

  3. Helsinki University Hospital Laboratory, Helsinki, Finland

    Mikael Skurnik

  4. Department of Virology, University of Turku, Helsinki, Finland

    Saija Kiljunen

Authors
  1. Mikael Skurnik
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  2. Maria Pajunen
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  3. Saija Kiljunen
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Correspondence to Mikael Skurnik.

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Skurnik, M., Pajunen, M. & Kiljunen, S. Biotechnological challenges of phage therapy. Biotechnol Lett 29, 995–1003 (2007). https://doi.org/10.1007/s10529-007-9346-1

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  • DOI: https://doi.org/10.1007/s10529-007-9346-1

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