A Study of the Myocardium Cell Membrane Using the Luo-Rudy Model
The Cell Electrophysiology Simulation Environment (CESE) modeling medium was used to study parameters of the myocardium cell membrane. The parameters of the model were experimentally tested using rectangular electric pulses. The growth of the transmembrane potential with respect to the resting potential increased the specific resistance, specific capacitance, and time constant τ m of the cell membrane. Comparative analysis revealed that the Weiss–Lapicque model provided most adequate description of reaction to rectangular defibrillation electric pulses.
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