Assortative Mating for Cigarette Smoking and for Alcohol Consumption in Female Australian Twins and their Spouses
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Non-random mating affects population variation for substance use and dependence. Developmentally, mate selection leading to positive spousal correlations for genetic similarity may result in increased risk for substance use and misuse in offspring. Mate selection varies by cohort and thus, assortative mating in one generation may produce marked changes in rates of substance use in the next. We aim to clarify the mechanisms contributing to spousal similarity for cigarette smoking and alcohol consumption.
Using data from female twins and their male spouses, we fit univariate and bivariate twin models to examine the contribution of primary assortative mating and reciprocal marital interaction to spousal resemblance for regular cigarette smoking and nicotine dependence, and for regular alcohol use and alcohol dependence.
We found that assortative mating significantly influenced regular smoking, regular alcohol use, nicotine dependence and alcohol dependence. The bivariate models for cigarette smoking and alcohol consumption also highlighted the importance of primary assortative mating on all stages of cigarette smoking and alcohol consumption, with additional evidence for assortative mating across the two stages of alcohol consumption.
Women who regularly used, and subsequently were dependent on cigarettes or alcohol were more likely to marry men with similar behaviors. After mate selection had occurred, one partner’s cigarette or alcohol involvement did not significantly modify the other partner’s involvement with these psychoactive substances.
KeywordsAssortative mating Smoking Drinking Multiple Stages Genetic
Supported by NIH grants DA12854 (PAFM), AA07535, AA11998, AA13221, AA07728, AA10248 (ACH) and DA019951 (MLP), and by a grant from the Alcoholic Beverages Medical Research Foundation (PAFM).
- Bierut LJ, Dinwiddie SH, Begleiter H, Crowe RR, Hesselbrock V, Nurnberger JI Jr, Porjesz B, Schuckit MA, Reich T (1998) Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism. Arch Gen Psychiatr 55:982–988CrossRefPubMedGoogle Scholar
- Crow JF, Felsenstein J (1982). The effect of assortative mating on the genetic composition of a population. Social Biol 15:85–97Google Scholar
- Eaves LJ, Last K, Martin NG, Jinks J (1977) A progressive approach tp the non-additivity and genotype-environmental covariance in the analysis of human differences. Br J Math Stat Psychol 30:1–42Google Scholar
- Fisher RA (1918) The correlation between relatives on the supposition of Mendelian inheritance. Trans Roy Soc Edinburgh 52:399–433Google Scholar
- Grant JD, Heath AC, Bucholz K, Madden PA, Martin NG, (2003) Assortative Mating or Spousal Influences on Alcoholism. Behav Genet 6:704Google Scholar
- Heath AC, Bucholz KK, Madden PA, Dinwiddie SH, Slutske WS, Bierut LJ, Statham DJ, Dunne MP, Whitfield JB, Martin NG (1997) Genetic and environmental contributions to alcohol dependence risk in a national twin sample: consistency of findings in women and men. Psychol Med 27:1381–1396CrossRefPubMedGoogle Scholar
- Heath AC, Martin NG, Eaves LJ (1984) Sense and nonsense in genetic epidemiology: a critique of the statistical model of Williams and Lyer. Acta Genet Med Gemellol (Roma) 33:557–563Google Scholar
- Ho HZ (1986) Assortative mating in unwed birth parents, adoptive, and nonadoptive parents. Social Biol 33:77–86Google Scholar
- Jencks C (1972) Inequality: a reassessment of the effect of family and schooling in America. Basic Books, New YorkGoogle Scholar
- Maes HH, Woodard CE, Murrelle L, Meyer JM, Silberg JL, Hewitt JK, Rutter M, Simonoff E, Pickles A, Carbonneau R, Neale MC, Eaves LJ (1999) Tobacco, alcohol and drug use in eight- to sixteen-year-old twins: the Virginia Twin Study of Adolescent Behavioral Development. J Stud Alcohol 60:293–305PubMedGoogle Scholar
- Neale MC (2004). Statistical modeling with Mx. Dept. of Psychiatry, Box # 980710, Richmond VA 23298Google Scholar
- Neale MC, Cardon LR (1992) Methodology for genetic studies of twins and families. Kluwer Academic Publishers, NetherlandsGoogle Scholar
- Price RA, Chen KH, Cavalli-Sforza LL, Feldman M (1981) Models of spousal influence and their application to smoking behavior. Social Biol 28:29Google Scholar
- Rimmer J, Winokur G (1972). The spouses of alcoholics: an example of assortative mating. Dis Nervous Syst 33:509–511Google Scholar
- SAS Institute (1999) SAS User Guide, Version 8.2. SAS Institute Inc, Cary, NCGoogle Scholar
- Substance Abuse and Mental Health Services Administration (SAMHSA) (2005). 2004 National Survey on Drug Use and HealthGoogle Scholar
- World Health Organization (1994). The composite international diagnostic interview, Version 1.1. Researcher’s manual. GenevaGoogle Scholar