Bulletin of Experimental Biology and Medicine

, Volume 167, Issue 6, pp 732–734 | Cite as

Platelet Chemiluminescence during Physical Exercise of Various Intensity

  • V. I. Sergienko
  • S. A. Kantyukov
  • E. N. ErmolaevaEmail author
  • S. L. Sashenkov
  • E. F. Surina-Marysheva
  • I. V. Medvedeva

Generation of ROS (including free radicals) in rat platelets during physical exercises of different intensities was evaluated by the chemiluminescent method. The acute or chronic submaximal exercises increased the platelet chemiluminescence by 2.5-3.0 times. In the control, platelet activation with physiological aggregant ADP enhanced their chemiluminescence by 7.5 times. Addition of ADP to platelets isolated from animals subjected to exercise of any intensity increased chemiluminescence by 4-5 times. In a trained organism, functional reserve of the platelets is preserved during long-term physical exercise of any intensity, but is exhausted after acute physical exercise. Thus, intensive physical exercises enhanced the hemostatic potential of the blood, which is associated with the risk of thrombohemorrhagic complications, especially in acute or submaximal long-term exercises.

Key Words

free radical oxidation platelets chemiluminescence physical exercise 


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • V. I. Sergienko
    • 1
  • S. A. Kantyukov
    • 2
  • E. N. Ermolaeva
    • 2
    Email author
  • S. L. Sashenkov
    • 2
  • E. F. Surina-Marysheva
    • 3
  • I. V. Medvedeva
    • 4
  1. 1.Federal Scientific Clinical Center of Physico-Chemical MedicineMoscowRussia
  2. 2.South-Ural State Medical UniversityMoscowRussia
  3. 3.South-Ural State UniversityChelyabinskRussia
  4. 4.Tyumen State Medical UniversityTyumenRussia

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