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Correction of Damaging Effects of Cisplatin-Containing Polychemotherapy on the Intestinal Epithelium with Tussilago farfara L. Polysaccharides

  • E. A. SafonovaEmail author
  • K. A. Lopatina
  • T. G. Razina
  • E. P. Zueva
  • L. A. Sadrikina
  • A. M. Gur’ev
  • M. V. Belousov
Article

A possibility for correction of damaging effects of polychemotherapy on the intestinal epithelium with Tussilago farfara L. polysaccharides was studied on C57Bl/6 mice with Lewis lung carcinoma. The polysaccharides had protective and/or stimulating effects on the intestinal epithelium during polychemotherapy and promoted reparative regeneration in the intestine.

Key Words

polychemotherapy polysaccharides intestinal epithelium toxicity 

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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • E. A. Safonova
    • 1
    Email author
  • K. A. Lopatina
    • 1
  • T. G. Razina
    • 1
  • E. P. Zueva
    • 1
  • L. A. Sadrikina
    • 1
  • A. M. Gur’ev
    • 2
  • M. V. Belousov
    • 2
  1. 1.E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical CenterTomskRussia
  2. 2.Siberian State Medical University, Ministry of Healthcare of the Russian FederationTomskRussia

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