Bulletin of Experimental Biology and Medicine

, Volume 167, Issue 2, pp 194–197 | Cite as

Contractile Activity of Lymph Nodes in Young, Middle-Aged, and Old Rats

  • G. A. Demchenko
  • S. N. Abdreshov
  • B. A. Nurmakhanova

We studied age-associated changes in contractile activity of isolated cervical and mesenteric lymph nodes in rats. In young and middle-aged rats, no significant changes in contractile activity of lymph nodes were revealed. In old rats, the amplitude of spontaneous contractions of lymph nodes was lower and their rate was higher than in young and middle-aged animals; the sensitivity of lymph nodes to vasoactive agents was reduced and the threshold of the response was higher in old rats.

Key Words

lymph nodes smooth muscles lymph node capsule 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • G. A. Demchenko
    • 1
  • S. N. Abdreshov
    • 1
  • B. A. Nurmakhanova
    • 1
  1. 1.Laboratory of Lymphatic System Physiology, Institute of Human and Animal PhysiologyMinistry of Education and Science of the Republic of KazakhstanAlmatyKazakhstan

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