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Bulletin of Experimental Biology and Medicine

, Volume 166, Issue 5, pp 610–612 | Cite as

Evaluation of Lipid Peroxidation—Antioxidant Defense System Depending on the Stage of Stress Reaction in Hypertensive ISIAH Rats

  • L. I. Kolesnikova
  • L. R. Kolesnikova
  • M. A. DarenskayaEmail author
  • L. V. Natyaganova
  • L. A. Grebenkina
  • L. I. Korytov
  • S. I. Kolesnikov
Article
  • 3 Downloads

The stages of stress reaction (anxiety and resistance) were reproduced on the model of stresssensitive hypertensive ISIAH rats. Analysis of the experimental data showed an increase in activity of the antioxidant defense system in ISIAH rats: total antioxidant activity of the blood and superoxide dismutase activity increased at the stage of anxiety and then decreased during the resistance stage.

Key Words

arterial hypertension oxidative stress stress reaction 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • L. I. Kolesnikova
    • 1
  • L. R. Kolesnikova
    • 1
    • 2
  • M. A. Darenskaya
    • 1
    Email author
  • L. V. Natyaganova
    • 1
  • L. A. Grebenkina
    • 1
  • L. I. Korytov
    • 2
  • S. I. Kolesnikov
    • 1
    • 3
  1. 1.Research Center for Family Health and Human Reproduction ProblemsIrkutskRussia
  2. 2.Irkutsk State Medical UniversityMinistry of Health of the Russian FederationIrkutskRussia
  3. 3.M. V. Lomonosov Moscow State UniversityMoscowRussia

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