Green Tea Extract Increases the Expression of Genes Responsible for Regulation of Calcium Balance in Rat Slow-Twitch Muscles under Conditions of Exhausting Exercise
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We studied the role of calcium-regulating structures of slow- (m. soleus, SOL) and fast-twitch (m. extensor digitorum longus, EDL) skeletal muscles of rats during adaptation to exhausting physical activity and the possibility of modulating this adaptation with decaffeinated green tea extract. It was established that EDL adaptation is mainly aimed at Са2+ elimination from the sarcoplasm by Са-ATPase and its retention in the reticulum by calsequestrin. Administration of green tea extract increased endurance due to involvement of slow-twitch muscles whose adaptation is associated with enhanced expression of all the studied genes responsible for the regulation of Ca2+ balance.
Key Wordsm. soleus m. extensor digitorum longus calcium exhausting exercise
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- 1.Minigalin AD, Voitenko NG, Vorobyov AA, Korf EA, Novozhilov AV, Petukhova OV, Baranova TI, Goncharov NV. Investigation of relations between physiological and biochemical parameters of human beings in dynamics after performing a maximal workload. Lech. Fizkult. Sport. Med. 2015;(6):14-18. Russian.Google Scholar
- 7.Goncharov N, Maevsky E, Voitenko N, Novozhilov A, Kubasov I, Jenkins R, Avdonin P. Nutraceuticals in sports activities and fatigue. Nutraceuticals: Efficacy, Safety and Toxicity. Gupta RC, ed. Amsterdam, 2016. P. 177-188.Google Scholar
- 14.Place N, Ivarsson N, Venckunas T, Neyroud D, Brazaitis M, Cheng AJ, Ochala J, Kamandulis S, Girard S, Volungevičius G, Paužas H, Mekideche A, Kayser B, Martinez-Redondo V, Ruas JL, Bruton J, Truffert A, Lanner JT, Skurvydas A, Westerblad H. Ryanodine receptor fragmentation and sarcoplasmic reticulum Ca2+ leak after one session of high-intensity interval exercise. Proc. Natl Acad. Sci. USA. 2015;112(50):15,492-15,497.CrossRefGoogle Scholar