Viscumin (mistletoe lectin I, MLI) in concentrations of 10—11-10—7 M causes endoplasmic reticulum stress and triggers unfolded protein response, a modulator of antitumor immunity, in target cells.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 163, No. 4, pp. 448-453, April, 2017
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Maltseva, D.V., Krainova, N.A., Khaustova, N.A. et al. Biodistribution of Viscumin after Subcutaneous Injection to Mice and In Vitro Modeling of Endoplasmic Reticulum Stress. Bull Exp Biol Med 163, 451–455 (2017). https://doi.org/10.1007/s10517-017-3826-7
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DOI: https://doi.org/10.1007/s10517-017-3826-7