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Bulletin of Experimental Biology and Medicine

, Volume 160, Issue 5, pp 632–634 | Cite as

Profile of microRNA in Blood Plasma of Healthy Humans

  • M. Yu. SkurnikovEmail author
  • Yu. A. Makarova
  • E. N. Knyazev
  • K. A. Fomicheva
  • K. M. Nyushko
  • E. K. Saribekyan
  • B. Ya. Alekseev
  • A. D. Kaprin
Article

Analysis of the plasma microRNA profile can be used for the diagnosis of various pathological and physiological conditions. Complete microRNA microprofiling is an extremely important task. Here we used microarray analysis allowing measurement of the expression of 2500 microRNA (MirBase, version 20). About 10% known microRNA were found in the plasma. Most of the detected microRNA (69 microRNA; ~30%) were encoded by mirtrons.

Key Words

microRNA blood plasma healthy volunteers 

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • M. Yu. Skurnikov
    • 1
    • 2
    Email author
  • Yu. A. Makarova
    • 1
    • 3
  • E. N. Knyazev
    • 2
  • K. A. Fomicheva
    • 1
  • K. M. Nyushko
    • 1
  • E. K. Saribekyan
    • 1
  • B. Ya. Alekseev
    • 1
  • A. D. Kaprin
    • 1
  1. 1.P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian FederationMoscowRussia
  2. 2.Bioclinicum Research and Engineering CenterMoscowRussia
  3. 3.V. A. Engelhard Institute of Molecular BiologyRussian Academy of SciencesMoscowRussia

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