Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity of mental shifts and immunopathogenetic factors in the studied patient population demonstrated the psychoneuroimmune nature of endometriosis.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 152, No. 7, pp. 100–105, July, 2011
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Nasyrova, R.F., Sotnikova, L.S., Baystrukova, N.V. et al. Psychoimmune Interactions in Women of Reproductive Age with Endometriosis. Bull Exp Biol Med 152, 93–97 (2011). https://doi.org/10.1007/s10517-011-1463-0
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DOI: https://doi.org/10.1007/s10517-011-1463-0