Bulletin of Experimental Biology and Medicine

, Volume 152, Issue 1, pp 93–97 | Cite as

Psychoimmune Interactions in Women of Reproductive Age with Endometriosis

  • R. F. Nasyrova
  • L. S. Sotnikova
  • N. V. Baystrukova
  • G. V. Krivoschchekova
  • V. V. Novitsky
  • I. E. Kupriyanova
  • V. Ya. Semke
  • I. O. Naslednikova
  • A. N. Baykov
Article

Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity of mental shifts and immunopathogenetic factors in the studied patient population demonstrated the psychoneuroimmune nature of endometriosis.

Key Words

psychoneuroimmunology mental disorders immune disorders endometriosis 

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References

  1. 1.
    E. K. Ailamazyan, M. I. Yarmolinskaya, N. Yu. Shved, et al., Vestn. Rossiisk. Voen. Med. Akad., No. 2, 16–22 (2009).Google Scholar
  2. 2.
    Yu. A. Aleksandrovskii and V. P. Chekhonin, Clinical Immunology of Borderline Mental Disorders [in Russian], Moscow (2005).Google Scholar
  3. 3.
    V. P. Baskakov, Yu. V. Tsvelev, and E. F. Kira, The Endometrioid Disease [in Russian], St. Petersburg (2002).Google Scholar
  4. 4.
    G. N. Kryzhanovskii, S. V. Magaeva, S. V. Makarov, et al., Neuroimmunopathology [in Russian], Moscow (2003).Google Scholar
  5. 5.
    D. M. Mendelevich and V. D. Mendelevich, Nevrol. Vestn., 25, Nos. 1–2, 104–108 (1993).Google Scholar
  6. 6.
    Psychotherapeutic Encyclopedia, Ed. B. D. Karvasarskii [in Russian], St. Petersburg (1998).Google Scholar
  7. 7.
    V. Ya. Semke, E. D. Schastnyi, and G. G. Simutkin, Affective Disorders [in Russian], Tomsk (2004).Google Scholar
  8. 8.
    H. O. Besedovsky and A. D. Rey, Brain Behav. Immun., 21, No. 1, 33–44 (2007).CrossRefGoogle Scholar
  9. 9.
    R. Dantzer, Ibid., 15, No. 1, 7–24 (2001).Google Scholar
  10. 10.
    M. R. Irwin, Ibid., 22, No. 2, 129–139 (2008).Google Scholar
  11. 11.
    M. R. Irwin and A. H. Miller, Ibid., 21, No. 4, 374–383 (2007).Google Scholar
  12. 12.
    G. Jones, C. Jenkinson, N. Taylor, et al., Hum. Reprod., 21, No. 10, 2686–2693 (2006).PubMedCrossRefGoogle Scholar
  13. 13.
    D. Kerr, C. Krishnan, M. L. Pucak, and J. Carmen, Int. Rev. Psychiatry, 17, No. 6, 443–449 (2005).PubMedCrossRefGoogle Scholar
  14. 14.
    E. L. Poleshuk, M. J. Bair, K. Kroenke, et al., Psychosomatics, 50, No. 3, 270–276 (2009).CrossRefGoogle Scholar
  15. 15.
    M. Rauchfuss, H. Kentenich, F. Siedentopf, and G. Danzer, J. Psychosom. Obstet. Gynaecol., 26, No. 2, 85–91 (2005).PubMedCrossRefGoogle Scholar
  16. 16.
    F. Siedentopf, N. Tariverdian, M. Rucke, et al., Am. J. Reprod. Immunol., 60, No. 5, 449–461 (2008).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • R. F. Nasyrova
    • 1
  • L. S. Sotnikova
    • 2
  • N. V. Baystrukova
    • 2
  • G. V. Krivoschchekova
    • 2
  • V. V. Novitsky
    • 2
  • I. E. Kupriyanova
    • 1
  • V. Ya. Semke
    • 1
  • I. O. Naslednikova
    • 2
  • A. N. Baykov
    • 2
  1. 1.Institute of Mental HealthSiberian Division of the Russian Academy of Medical SciencesTomskRussia
  2. 2.Siberian State Medical University, Federal Agency for Health Care and Social DevelopmentTomskRussia

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