Bulletin of Experimental Biology and Medicine

, Volume 152, Issue 1, pp 5–8 | Cite as

Catecholamines, α-, and β-Adrenoceptors Are Not Responsible for Activation of Duodenum Motility Induced by Sympathetic Nerve Stimulation

  • D. S. Sveshnikov
  • V. M. Smirnov
  • I. L. Myasnikov
  • M. I. Mongush
  • I. A. Yurasova
Article
  • 49 Downloads

Stimulation of sympathetic nerve in anesthetized dogs not treated with adrenergic blockers more frequently exerted stimulating rather than inhibitory effect on duodenal motility. Blockade of α- and β-adrenoceptors with phentolamine and propranolol, respectively, did not prevent the excitatory action of the sympathetic nerve stimulation, but even potentiated this effect. The data showed that catecholamines as well as α- and β-adrenoceptors are not involved in the excitatory effect of sympathetic origin.

Key Words

duodenum neural control catecholamines α- and β-adrenoceptors 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    V. M. Smirnov, Byull. Eksp. Biol. Med., 112, No. 9, 229–231 (1991).Google Scholar
  2. 2.
    V. M. Smirnov, V. A. Klevtsov, and A. E. Lychkova, Ross. Fiziol. Zh., 72, No. 5, 650–655 (1986).Google Scholar
  3. 3.
    V. M. Smirnov, V. A. Klevtsov, N. A. Smirnova, and A. E. Lychkova, Byull. Eksp. Biol. Med., 104, No. 9, 270–273 (1987).Google Scholar
  4. 4.
    E. Bathon and H. Ormsbee, Gastroenterology, 78, No. 5, Pt. 2, 1528–1600 (1980).Google Scholar
  5. 5.
    D. Delbro and B. Lisander, Acta Physiol. Scand., 110, No. 2, 137–144 (1980).PubMedCrossRefGoogle Scholar
  6. 6.
    J. E. Gillespie and B. R. Mackenna, J. Physiol., 156, No. 1, 17–34 (1961).PubMedGoogle Scholar
  7. 7.
    B. Hoffmann, Lange Medical Books, Ed. B. Katzung, 6th ed., 1995, pp. 115–146.Google Scholar

Copyright information

© Springer Science+Business Media, Inc. 2011

Authors and Affiliations

  • D. S. Sveshnikov
    • 1
  • V. M. Smirnov
    • 1
  • I. L. Myasnikov
    • 1
  • M. I. Mongush
    • 1
  • I. A. Yurasova
    • 1
  1. 1.Department of PhysiologyN. I. Pirogov Russian State Medical UniversityMoscowRussia

Personalised recommendations