Blood Levels of Inflammatory and Destructive Biomarkers in Coronary Atherosclerosis of Different Severity
- 50 Downloads
In male patients with coronary atherosclerosis without acute coronary syndrome, the levels of inflammatory-destructive biomarkers of atherosclerotic plaque instability depended on the severity and dissemination of coronary atherosclerosis. The highest levels of C-reactive protein and matrix metalloproteinase 3 were found in men with atherosclerotic involvement of all three main coronary arteries, primarily their middle and distal segments, and in men with predominance of low-grade stenoses (<50%) of coronary arteries in areas of atherosclerotic plaques.
Key Wordscoronary atherosclerosis biomarkers of atherosclerotic plaque instability highly sensitive C-reactive protein metalloproteinases
Unable to display preview. Download preview PDF.
- 1.Yu. I. Ragino, A. M. Cherjyavski, Ya. V. Polonskaja, et al., Byull. Eksp. Biol. Med., 144, No. 11, 500–503 (2007).Google Scholar
- 2.Yu. I. Ragino, A. M. Chernjavski, Ya. V. Polonskaja, et al., Kardiologiya, No. 9, 62–67 (2007).Google Scholar
- 7.J. C. Fruchart, Handbook of Dyslipidemia and Atherosclerosis. France, University of Lille (2003), Pt. 1. pp. 1–65.Google Scholar
- 13.P. K. Shah, High-Risk Atherosclerotic Plaques: Mechanisms, Imaging, Models, and Therapy. Ed. L. M. Khachigian, New York (2005), pp. 1–19.Google Scholar
- 14.P. K. Shah and B. Sharifi , Biochemistry of Atherosclerosis, Ed. S. K. Cheema, New York (2006), pp. 455–563.Google Scholar
- 15.R. Waksman and P. W. Seruys, Handbook of the Vulnerable Plaque. London (2004), pp. 1–48.Google Scholar