Blood Levels of Inflammatory and Destructive Biomarkers in Coronary Atherosclerosis of Different Severity
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In male patients with coronary atherosclerosis without acute coronary syndrome, the levels of inflammatory-destructive biomarkers of atherosclerotic plaque instability depended on the severity and dissemination of coronary atherosclerosis. The highest levels of C-reactive protein and matrix metalloproteinase 3 were found in men with atherosclerotic involvement of all three main coronary arteries, primarily their middle and distal segments, and in men with predominance of low-grade stenoses (<50%) of coronary arteries in areas of atherosclerotic plaques.
Key Wordscoronary atherosclerosis biomarkers of atherosclerotic plaque instability highly sensitive C-reactive protein metalloproteinases
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