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Effect of Delta-Sleep-Inducing Peptide on Expression of Heat Shock Protein 70 kDa in K562 Cells

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

For evaluation of the stress-protective influence of delta-sleep inducing peptide we studied its effects on the system of heat-shock proteins in immune cells using the method of flow cytometry. The peptide affected the expression of heat-shock protein 70 kDa in cultured human myeloleukemia K562 cells. Delta-sleep-inducing peptide reduces accumulation of intracellular heat shock proteins 70 kDa in cells cultured under conditions of high density.

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Authors and Affiliations

  1. M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia

    A. A. Nurbakov, I. I. Mikhaleva & A. M. Sapozhnikov

Authors
  1. A. A. Nurbakov
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  2. I. I. Mikhaleva
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  3. A. M. Sapozhnikov
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Correspondence to A. A. Nurbakov.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 147, No. 1, pp. 40-42, January, 2009

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Nurbakov, A.A., Mikhaleva, I.I. & Sapozhnikov, A.M. Effect of Delta-Sleep-Inducing Peptide on Expression of Heat Shock Protein 70 kDa in K562 Cells. Bull Exp Biol Med 147, 39–41 (2009). https://doi.org/10.1007/s10517-009-0453-y

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  • DOI: https://doi.org/10.1007/s10517-009-0453-y

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