Bulletin of Experimental Biology and Medicine

, Volume 143, Issue 6, pp 713–717

Analysis of antibiotic resistance markers in Chlamydia trachomatis clinical isolates obtained after ineffective antibiotic therapy

  • M. M. Shkarupeta
  • V. N. Lazarev
  • T. A. Akopian
  • T. S. Afrikanova
  • V. M. Govorun
Article

DOI: 10.1007/s10517-007-0221-9

Cite this article as:
Shkarupeta, M.M., Lazarev, V.N., Akopian, T.A. et al. Bull Exp Biol Med (2007) 143: 713. doi:10.1007/s10517-007-0221-9

Abstract

Antibiotic resistance markers were analyzed in C. trachomatis clinical isolates obtained after ineffective therapy of urogenital chlamydiasis with fluoroquinolones and macrolides. Heterotypical resistance to fluoroquinolones and macrolides was detected in all clinical isolates. No significant mutations in the target genes were detected.

Key Words

Chlamydia trachomatis antibiotic resistance markers heterotypical resistance 

Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • M. M. Shkarupeta
    • 1
  • V. N. Lazarev
    • 1
  • T. A. Akopian
    • 1
  • T. S. Afrikanova
    • 1
  • V. M. Govorun
    • 1
  1. 1.Institute of Physicochemical MedicineFederal Agency for Health Care and Social DevelopmentMoscow

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