Bulletin of Experimental Biology and Medicine

, Volume 141, Issue 1, pp 26–29 | Cite as

Short-term cold exposure improves antioxidant status and general resistance of animals

  • M. Ya. Akhalaya
  • A. G. Platonov
  • A. A. Baizhumanov
Biophysics and Biochemistry


We studied the effect of short-term swimming in cold water (13°C) on parameters of the blood antioxidant system (activities of superoxide dismutase and catalase, concentrations of ceruloplasmin and nonprotein thiols), heme oxygenase activity, and nonprotein thiol level in mouse liver. The test parameters of antioxidant protection increased 1 h after cold exposure and remained high 1 day after treatment. These changes were accompanied by an increase in the adaptive capacity. After swimming in cold water the resistance of animals to another stress factor (administration of epinephrine) was higher compared to controls.

Key Words

cold stress superoxide dismutase ceruloplasmin catalase nonprotein thiols 


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • M. Ya. Akhalaya
    • 1
  • A. G. Platonov
    • 1
  • A. A. Baizhumanov
    • 1
  1. 1.Laboratory of Radiation Biophysics, Department of Biophysics, Biological FacultyM. V. Lomonosov Moscow State UniversityRussia

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