Parents’ Perspectives About Adolescent Boys’ Involvement in Biomedical HIV Prevention Research

  • Brian Mustanski
  • Kathryn Macapagal
  • Matthew Thomann
  • Brian A. Feinstein
  • Michael E. Newcomb
  • Darnell Motley
  • Celia B. Fisher
Original Paper

Abstract

Research on the use of pre-exposure prophylaxis (PrEP) among adolescents at high risk for HIV is urgently needed, and parents’ perspectives on these studies are essential for guiding the responsible conduct of adolescent PrEP research. We conducted interviews with 30 parents of adolescent boys (50% known/presumed heterosexual; 50% sexual minority) to understand their views of research risks and benefits and parental permission regarding their son’s involvement in a hypothetical PrEP adherence trial. Parents identified several health and educational benefits of the study and expressed that waiving parental permission would overcome barriers to accessing PrEP, particularly for youth who may benefit most. Among their concerns were medication non-adherence and risk compensation. Parents provided suggestions to facilitate informed, rational, and voluntary participation decisions and protect youth’s safety if parental permission was waived. These findings can inform ways to increase parental trust in PrEP research and create adequate protections for adolescent participants.

Keywords

HIV prevention Pre-exposure prophylaxis Parents Adolescents Men who have sex with men 

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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  1. 1.Department of Medical Social Sciences, Institute for Sexual and Gender Minority Health and WellbeingNorthwestern UniversityChicagoUSA
  2. 2.Department of Anthropology and SociologyKalamazoo CollegeKalamazooUSA
  3. 3.Psychology ServiceEdward Hines, Jr. VA Medical CenterHinesUSA
  4. 4.Department of Psychology, Center for Ethics EducationFordham UniversityBronxUSA

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