, 14:969 | Cite as

Cracking open cell death in the Drosophila ovary

  • Tracy L. Pritchett
  • Elizabeth A. Tanner
  • Kimberly McCall
Apoptosis in Drosophila


The Drosophila melanogaster ovary is a powerful yet simple system with only a few cell types. Cell death in the ovary can be induced in response to multiple developmental and environmental signals. These cell deaths occur at distinct stages of oogenesis and involve unique mechanisms utilizing apoptotic, autophagic and perhaps necrotic processes. In this review, we summarize recent progress characterizing cell death mechanisms in the fly ovary.


Drosophila Oogenesis Apoptosis Autophagy Caspase Insulin 



We thank Jeanne Peterson and Christy Li for comments on the manuscript, and Horacio Frydman and members of our lab for helpful discussions. Supported by NIH grant R01 GM60574 (KM).


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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Tracy L. Pritchett
    • 1
  • Elizabeth A. Tanner
    • 2
  • Kimberly McCall
    • 1
  1. 1.Department of BiologyBoston UniversityBostonUSA
  2. 2.Molecular Biology, Cell Biology, and Biochemistry ProgramBoston UniversityBostonUSA

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