A Pilot Study of Neurofeedback for Chronic PTSD
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EEG Biofeedback (also known as neurofeedback) has been in use as a clinical intervention for well over 30 years; however, it has made very little impact on clinical care. One reason for this has been the difficulty in designing research to measure clinical change in the real world. While substantial evidence exists for its efficacy in treating attention deficit/hyperactivity disorder, relatively little evidence exists for its utility in other disorders including posttraumatic stress disorder (PTSD). The current study represents a “proof-of-concept” pilot for the use of neurofeedback with multiply-traumatized individuals with treatment-resistant PTSD. Participants completed 40 sessions of neurofeedback training two times per week with sensors randomly assigned (by the study coordinator, who was not blind to condition) to sensor placements of either T4-P4 or T3-T4. We found that neurofeedback significantly reduced PTSD symptoms (Davidson Trauma Scale scores averaged 69.14 at baseline to 49.26 at termination), and preceded gains in affect regulation (Inventory of Altered Self-Capacities-Affect Dysregulation scores averaged 23.63 at baseline to 17.20 at termination). We discuss a roadmap for future research.
KeywordsEEG biofeedback Neurofeedback Treatment outcome Posttraumatic stress disorder Complex trauma
Richard Jacobson, Ilya Yacevich, Regina Musicaro, Marla Zucker Ph.D., Hilary Hogdon Ph.D., Janice Stubblefield. This study was supported by a Grant from the ANS Foundation.
- Aderka, I. M., Foa, E. B., Applebaum, E., Shafran, N., & Gilboa-Schechtman, E. (2011). Direction of influence between posttraumatic and depressive symptoms during prolonged exposure therapy among children and adolescents. Journal of Consulting and Clinical Psychology, 79(3), 421–425.CrossRefPubMedPubMedCentralGoogle Scholar
- Georgopoulos, A. P., Tan, H. R. M., Lewis, S. M., Leuthold, A. C., Winskowski, A. M., Lynch, J. K., et al. (2010). The synchronous neural interactions test as a functional neuromarker for post-traumatic stress disorder (PTSD): A robust classification method based on the bootstrap. Journal of Neural Engineering, 7(1), 016011.CrossRefGoogle Scholar
- Institute of Medicine. (2001). Small clinical trials: Issues and challenges. Washington, DC: National Academy Press.Google Scholar
- Jonas, D. E., Cusack, K., Forneris, C. A., Wilkins, T. M., Sonis, J., Cook Middleton, J. et al. (2013). Psychological and pharmacological treatments for adults with posttraumatic stress disorder (PTSD). Comparative Effectiveness Reviews, 92. Retrieved from http://www.ncbi.nlm.nih.gov/books/NBK137702/ website.
- Lanius, R. A., Williamson, P. C., Boksman, K., Densmore, M., Gupta, M., Neufeld, R. W. J., et al. (2002). Brain activation during script-driven imagery induced dissociative responses in PTSD: A functional magnetic resonance imaging investigation. Biological Psychiatry, 52(4), 305–311.CrossRefPubMedGoogle Scholar
- Peniston, E. G., & Kulkosky, P. J. (1991). Alpha-theta brainwave neurofeedback for Vietnam veterans with combat-related post-traumatic stress disorder. Medical Psychotherapy, 4(1), 47–60.Google Scholar
- Rauch, S. L., van der Kolk, B. A., Fisler, R. E., Alpert, N. M., Orr, S. P., Savage, C. R., et al. (1996). A symptom provocation study of posttraumatic stress disorder using positron emission tomography and script-driven imagery. Archives of General Psychiatry, 53, 380–387.CrossRefPubMedGoogle Scholar
- Raudenbush, S. W., Bryk, A. S., & Congdon, R. (2005). HLM 6.0: Hierarchical linear modeling. Lincolnwood, IL: Scientific Software International.Google Scholar
- Shin, L. M., Orr, S., Carson, M. A., Rauch, R. L., Macklin, M. L., Lasko, N. B., et al. (2004). Regional cerebral blood flow in the amygdala and medial prefrontal cortex during traumatic imagery in male and female Vietnam veterans with PTSD. Archives of General Psychiatry, 61, 168–176.CrossRefPubMedGoogle Scholar
- Sonuga-Barke, E. J., Brandeis, D., Cortese, S., Daley, D., Ferrin, M., Holtmann, M., et al. (2013). Nonpharmacological interventions for ADHD: Systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. American Journal of Psychiatry, 170, 275–289.CrossRefPubMedGoogle Scholar
- Suvak, M. K., Walling, S. M., Iverson, K. M., Taft, C. T., & Resick, P. A. (2009). Multilevel regression analyses to investigate the relationship between two variables over time: Examining the longitudinal association between intrusion and avoidance. Journal of Traumatic Stress, 22(6), 622–631.PubMedGoogle Scholar
- Zelazo, P. D., & Cunningham, W. A. (2007). Executive function: Mechanisms underlying emotion regulation. In J. J. Gross (Ed.), Handbook of emotion regulation (pp. 135–158). New York: Guilford Press.Google Scholar