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Applied Psychophysiology and Biofeedback

, Volume 32, Issue 1, pp 1–10 | Cite as

A Pilot Study of the Efficacy of Heart Rate Variability (HRV) Biofeedback in Patients with Fibromyalgia

  • Afton L. HassettEmail author
  • Diane C. Radvanski
  • Evgeny G. Vaschillo
  • Bronya Vaschillo
  • Leonard H. Sigal
  • Maria Katsamanis Karavidas
  • Steven Buyske
  • Paul M. Lehrer
Original Paper

Abstract

Fibromyalgia (FM) is a non-inflammatory rheumatologic disorder characterized by musculoskeletal pain, fatigue, depression, cognitive dysfunction and sleep disturbance. Research suggests that autonomic dysfunction may account for some of the symptomatology of FM. An open label trial of biofeedback training was conducted to manipulate suboptimal heart rate variability (HRV), a key marker of autonomic dysfunction. Methods: Twelve women ages 18–60 with FM completed 10 weekly sessions of HRV biofeedback. They were taught to breathe at their resonant frequency (RF) and asked to practice twice daily. At sessions 1, 10 and 3-month follow-up, physiological and questionnaire data were collected. Results: There were clinically significant decreases in depression and pain and improvement in functioning from Session 1 to a 3-month follow-up. For depression, the improvement occurred by Session 10. HRV and blood pressure variability (BPV) increased during biofeedback tasks. HRV increased from Sessions 1–10, while BPV decreased from Session 1 to the 3 month follow-up. Conclusions: These data suggest that HRV biofeedback may be a useful treatment for FM, perhaps mediated by autonomic changes. While HRV effects were immediate, blood pressure, baroreflex, and therapeutic effects were delayed. This is consistent with data on the relationship among stress, HPA axis activity, and brain function.

Keywords

Heart rate variability Biofeedback Fibromyalgia Depression Pain Breathing 

Notes

Acknowledgments

We thank the patients with FM from the Rheumatology clinic at Robert Wood Johnson Medical School for their willingness to assist us with our research. We also remain grateful to the Arthritis Foundation, especially the New Jersey Chapter, for their ongoing support of this and other HRV biofeedback research for patients with FM. Finally, we would like to thank the anonymous reviewers for their helpful contributions to the text of this paper.

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Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Afton L. Hassett
    • 1
    Email author
  • Diane C. Radvanski
    • 1
  • Evgeny G. Vaschillo
    • 2
  • Bronya Vaschillo
    • 2
  • Leonard H. Sigal
    • 1
    • 3
  • Maria Katsamanis Karavidas
    • 4
  • Steven Buyske
    • 5
  • Paul M. Lehrer
    • 4
  1. 1.Department of MedicineDivision of Rheumatology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School (UMDNJ-RWJMS)New BrunswickUSA
  2. 2.Center of Alcohol StudiesRutgers University PiscatawayPiscatawayUSA
  3. 3.Pharmaceutical Research InstitutePrincetonUSA
  4. 4.Department of PsychiatryUMDNJ-RWJMSPiscatawayUSA
  5. 5.Department of StatisticsRutgers UniversityPiscatawayUSA

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