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Alcohol Misuse and Illicit Drug Use Among Occupational Groups at High Risk of HIV in Sub-Saharan Africa: A Systematic Review

  • Monica O. KuteesaEmail author
  • Janet Seeley
  • Helen A. Weiss
  • Sarah Cook
  • Anatoli Kamali
  • Emily L. Webb
Original Paper
  • 57 Downloads

Abstract

Key occupational groups in sub-Saharan Africa (SSA) are at increased risk of HIV, and may be at increased risk of substance use. In January 2018, we systematically searched for studies reporting prevalence of, and risk factors for alcohol misuse or illicit drug use and their association with HIV incidence or prevalence among fisherfolk, uniformed personnel, truckers, miners, motorcycle taxi riders and sex workers in SSA. Seventy-one studies published between 1983 and 2017 were included: 35 reported on alcohol misuse (19 using AUDIT, 5 using CAGE) and 44 on illicit drug use (eight reported both). Median prevalence of alcohol misuse based on AUDIT/CAGE was 32.8% (IQR 20.8–48.5%). Prevalence of illicit drug use ranged from 0.1% (95% CI: 0.0–0.2%) for injection drug use to 97.1% (95% CI: 85.1–99.9%) for khat (among uniformed personnel). Among papers examining associations between substance use and HIV incidence (n = 3) or prevalence (n = 14), nine papers (53%) reported a significant positive association (2 with incidence, 7 with prevalence). Harm reduction interventions in occupational settings are urgently required to prevent new HIV infections.

Keywords

Alcohol misuse Illicit drug use HIV Key populations Sub-Saharan Africa 

Notes

Acknowledgements

We sincerely thank Matt Price M.D for constructive criticism of the manuscript.

Authors’ Contributions

All authors have made substantial contributions to the work reported in the manuscript. MOK devised the project, MOK, JAS, AK, HAW, SC, and EW contributed to the design of the research, MOK and EW to the data extraction and analysis of the results and to the writing of the manuscript. JAS, AK, HAW, and SC discussed the results and contributed to the manuscript.

Funding

This research was jointly funded by the UK Medical Research Council (MRC) and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement. E Webb and H Weiss received funding from MRC Grant Reference MR/K012126/1.

Compliance with Ethical Standards

The review protocol was registered at: (http://www.crd.york.ac.uk/PROSPERO CRD42016053495).

Conflict of interest

The authors have declared that no competing interests exist.

Supplementary material

10461_2019_2483_MOESM1_ESM.docx (46 kb)
Supplementary material 1 (DOCX 46 kb)

References

  1. 1.
    UNAIDS. State of the epidemic 2018. http://www.unaids.org/sites/default/files/media_asset/unaids-data-2018_en.pdf. Accessed 14 Dec 2018.
  2. 2.
    Human Sciences Research Council. South African National HIV Prevalence, Incidence, Behaviour and Communication Survey 2017. http://www.hsrc.ac.za/en/media-briefs/hiv-aids-stis-and-tb/sabssm-launch-2018. Accessed 10 Nov 2018.
  3. 3.
    World Health Organisation. Global status report on alcohol and health. Geneva: Switzerland; 2014.Google Scholar
  4. 4.
    Dewing S, Plüddemann A, Myers BJ, Parry CD. Review of injection drug use in six African countries: Egypt, Kenya, Mauritius, Nigeria, South Africa and Tanzania. Drugs Educ Prev Policy. 2006;13(2):121–37.CrossRefGoogle Scholar
  5. 5.
    Beckerleg S, Telfer M, Hundt GL. The rise of injecting drug use in east Africa: a case study from Kenya. Harm Reduct J. 2005;2(1):1.CrossRefGoogle Scholar
  6. 6.
    Acuda W, Othieno CJ, Obondo A, Crome IB. The epidemiology of addiction in Sub-Saharan Africa: a synthesis of reports, reviews, and original articles. Am J Addict. 2011;20(2):87–99.PubMedGoogle Scholar
  7. 7.
    Teodoro E BM, Sema Baltazar C, Young P, Frank H, Sathane I, et al., editor Urgent need for harm reduction interventions in Mozambique: results from the Integrated Biological and Behavioral Surveillance Survey among people who inject drugs. IAS 2015, Vancouver, Canada; 2015.Google Scholar
  8. 8.
    PEPFAR. FY 2015 Mozambique Country Operational Plan (COP). Washington, DC; 2015.Google Scholar
  9. 9.
    Matiko E, Khatib A, Khalid F, et al. HIV prevalence and risk behaviors among people who inject drugs in two serial cross-sectional respondent-driven sampling surveys, Zanzibar 2007 and 2012. AIDS Behav. 2015;19(1):36–45.CrossRefGoogle Scholar
  10. 10.
    Scribner R, Theall KP, Simonsen N, Robinson W. HIV risk and the alcohol environment: advancing an ecological epidemiology for HIV/AIDS. Alcohol Res Health. 2010;33(3):179.PubMedPubMedCentralGoogle Scholar
  11. 11.
    Williams EC, Hahn JA, Saitz R, Bryant K, Lira MC, Samet JH. Alcohol use and human immunodeficiency virus (HIV) infection: current knowledge, implications, and future directions. Alcohol Clin Exp Res. 2016;40(10):2056–72.CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Monroe AK, Lau B, Mugavero MJ et al. Heavy Alcohol Use Is Associated With Worse Retention in HIV Care. J Acquir Immune Defic Syndr. (1999). 2016;73(4):419–25.Google Scholar
  13. 13.
    Hahn JA, Samet JH. Alcohol and HIV disease progression: weighing the evidence. Curr HIV-AIDS. 2010;7(4):226–33.CrossRefGoogle Scholar
  14. 14.
    Samet JH, Cheng DM, Libman H, Nunes DP, Alperen JK, Saitz R. Alcohol consumption and HIV disease progression. JAIDS (1999). 2007;46(2):194.Google Scholar
  15. 15.
    Kumar S, Jin M, Ande A, Sinha N, Silverstein PS, Kumar A. Alcohol consumption effect on antiretroviral therapy and HIV-1 pathogenesis: role of cytochrome P450 isozymes. Expert Opin Drug Metab Toxicol. 2012;8(11):1363–75.CrossRefPubMedPubMedCentralGoogle Scholar
  16. 16.
    Hendershot CS, Stoner SA, Pantalone DW, Simoni JM. Alcohol use and antiretroviral adherence: review and meta-analysis. JAIDS. 2009;52(2):180.PubMedGoogle Scholar
  17. 17.
    DeLorenze GN, Weisner C, Tsai AL, Satre DD, Quesenberry CP Jr. Excess mortality among HIV-infected patients diagnosed with substance use dependence or abuse receiving care in a fully integrated medical care program. Alcohol Clin Exp Res. 2011;35(2):203–10.CrossRefPubMedGoogle Scholar
  18. 18.
    Neblett RC, Hutton HE, Lau B, McCaul ME, Moore RD, Chander G. Alcohol consumption among HIV-infected women: impact on time to antiretroviral therapy and survival. Int J Womens Health. 2011;20(2):279–86.CrossRefGoogle Scholar
  19. 19.
    Hahn JA, Cheng DM, Emenyonu NI, et al. Alcohol use and HIV disease progression in an antiretroviral naive cohort. JAIDS. 2018;77(5):492–501.PubMedGoogle Scholar
  20. 20.
    Weiss HA, Vandepitte J, Bukenya JN, et al. High levels of persistent problem drinking in women at high risk for HIV in Kampala, Uganda: a prospective cohort study. Int J Environ Res Public Health. 2016;13(2):153.CrossRefPubMedPubMedCentralGoogle Scholar
  21. 21.
    Li Q, Li X, Stanton B. Alcohol use among female sex workers and male clients: an integrative review of global literature. Alcohol Alcohol. 2010;45(2):188–99.CrossRefPubMedPubMedCentralGoogle Scholar
  22. 22.
    Kissling E, Allison EH, Seeley JA, et al. Fisherfolk are among groups most at risk of HIV: cross-country analysis of prevalence and numbers infected. AIDS. 2005;19(17):1939–46.CrossRefPubMedGoogle Scholar
  23. 23.
    Kiwanuka N, Ssetaala A, Nalutaaya A, et al. High incidence of HIV-1 infection in a general population of fishing communities around Lake Victoria, Uganda. PLoS ONE. 2014;9(5):e94932.CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Bakari M, Lyamuya E, Mugusi F, et al. The prevalence and incidence of HIV-1 infection and syphilis in a cohort of police officers in Dar es Salaam, Tanzania: a potential population for HIV vaccine trials. AIDS. 2000;14(3):313–20.CrossRefPubMedGoogle Scholar
  25. 25.
    Sagaon-Teyssier L, Balique H, Diallo F, et al. Prevalence of HIV at the Kokoyo informal gold mining site: what lies behind the glitter of gold with regard to HIV epidemics in Mali? A community-based approach (The ANRS-12339 Sanu Gundo cross-sectional survey). BMJ Open. 2017;7(8):e016558.CrossRefPubMedPubMedCentralGoogle Scholar
  26. 26.
    Crush J. Migration-induced HIV and AIDS in Rural Mozambique and Swaziland. Oxford: African Books Collective; 2010.Google Scholar
  27. 27.
    Lindan CP, Anglemyer A, Hladik W, et al. High-risk motorcycle taxi drivers in the HIV/AIDS era: a respondent-driven sampling survey in Kampala, Uganda. Int J STD AIDS. 2015;26(5):336–45.CrossRefPubMedGoogle Scholar
  28. 28.
    Delany-Moretlwe S, Bello B, Kinross P, et al. HIV prevalence and risk in long-distance truck drivers in South Africa: a national cross-sectional survey. Int J STD AIDS. 2014;25(6):428–38.CrossRefPubMedGoogle Scholar
  29. 29.
    Vandepitte J, Bukenya J, Weiss HA, et al. HIV and other sexually transmitted infections in a cohort of women involved in high-risk sexual behavior in Kampala, Uganda. Sex Transm Infect. 2011;38(4):316–23.Google Scholar
  30. 30.
    Lowndes CM, Alary M, Meda H, et al. Role of core and bridging groups in the transmission dynamics of HIV and STIs in Cotonu, Benin, West Africa. Sex Transm Infect. 2002;78:i69–77.CrossRefPubMedPubMedCentralGoogle Scholar
  31. 31.
    UNAIDS. Fast track. Ending the epidemic by 2030. 2014. http://www.unaids.org/sites/default/files/media_asset/JC2686_WAD2014report_en.pdf. Accessed 16 June 2016.
  32. 32.
    Lubega M, Nakyaanjo N, Nansubuga S, et al. Risk denial and socio-economic factors related to high HIV transmission in a fishing community in Rakai, Uganda: a qualitative study. PLoS ONE. 2015;10(8):e0132740.CrossRefPubMedPubMedCentralGoogle Scholar
  33. 33.
    Pithey A, Parry C. Descriptive systematic review of sub-Saharan African studies on the association between alcohol use and HIV infection. SAHARA-J. 2009;6(4):155–69.CrossRefPubMedGoogle Scholar
  34. 34.
    Fisher JC, Bang H, Kapiga SH. The association between HIV infection and alcohol use: a systematic review and meta-analysis of African studies. Sex Transm Dis. 2007;34:856–63.CrossRefPubMedGoogle Scholar
  35. 35.
    Francis JM, Grosskurth H, Changalucha J, Kapiga SH, Weiss HA. Systematic review and meta-analysis: prevalence of alcohol use among young people in eastern Africa. Trop Med Int Health. 2014;19(4):476–88.CrossRefPubMedPubMedCentralGoogle Scholar
  36. 36.
    Smolak A. A meta-analysis and systematic review of HIV risk behavior among fishermen. AIDS Care. 2014;26(3):282–91.CrossRefPubMedGoogle Scholar
  37. 37.
    Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews of interventions. Version 5.1.0 [updated July 2018]. 2018. http://handbook.cochrane.org. Accessed 31 Oct 2018.
  38. 38.
    Preferred Reporting Items for Systematic Reviews and Meta-Analyses. 2015. http://www.prisma-statement.org/. Accessed 14 Oct 2016.
  39. 39.
    Babor TF, Higgins-Biddle JC, Saunders JB, Monteiro MG, World Health Organization. AUDIT: the alcohol use disorders identification test: guidelines for use in primary health care. 2001.Google Scholar
  40. 40.
    Babor TF, Robaina K. The Alcohol Use Disorders Identification Test (AUDIT): a review of graded severity algorithms and national adaptations. Int J Alcohol Drug Res. 2016;5(2):17–24.CrossRefGoogle Scholar
  41. 41.
    Bush K, Kivlahan DR, McDonell MB, Fihn SD, Bradley KA. The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Arch Intern Med. 1998;158(16):1789–95.CrossRefPubMedGoogle Scholar
  42. 42.
    O’Brien CP. The cage questionnaire for detection of alcoholism. JAMA. 2008;300(17):2054–6.CrossRefPubMedGoogle Scholar
  43. 43.
    Wittchen H, Semler G. CIDI-Composite International Diagnostic Interview. Beltz Test Weinheim Google Scholar. 1990.Google Scholar
  44. 44.
    Association AP. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: American Psychiatric Association; 2000.Google Scholar
  45. 45.
    Sileo KM. Engagement in HIV Care among Male Fisherfolk in Uganda (Doctoral dissertation). San Diego State University, ProQuest Dissertations Publishing. UMI No. 10689344. 2017.Google Scholar
  46. 46.
    Ihunwo AO, Kayanja FI, Amadi-Ihunwo UB. Use and perception of the psychostimulant, khat (Catha edulis) among three occupational groups in South Western Uganda. East Afr Med J. 2004;81(9):468–73.CrossRefPubMedGoogle Scholar
  47. 47.
    Johnston LG, Corceal S. Unexpectedly high injection drug use, HIV and hepatitis C prevalence among female sex workers in the Republic of Mauritius. AIDS Behav. 2013;17(2):574–84.CrossRefPubMedGoogle Scholar
  48. 48.
    Gorbach PM, Sopheab H, Phalla T, et al. Sexual bridging by Cambodian men: potential importance for general population spread of STD and HIV epidemics. Sex Transm Infect. 2000;27(6):320–6.CrossRefGoogle Scholar
  49. 49.
    Schneider M, Chersich M, Neuman M, Parry C. Alcohol consumption and HIV/AIDS: the neglected interface. Addiction. 2012;107(8):1369–71.CrossRefPubMedGoogle Scholar
  50. 50.
    Strathdee SA, Hallett TB, Bobrova N, et al. HIV and risk environment for injecting drug users: the past, present, and future. The Lancet. 2010;376(9737):268–84.CrossRefGoogle Scholar
  51. 51.
    Kissling E, Allison EH, Seeley JA, et al. Fisherfolk are among groups most at risk of HIV: cross-country analysis of prevalence and numbers infected. AIDS. 2005;19(17):1939–46.CrossRefPubMedGoogle Scholar
  52. 52.
    LʼEngle KL, Mwarogo P, Kingola N, Sinkele W, Weiner DH. A randomized controlled trial of a brief intervention to reduce alcohol use among female sex workers in Mombasa. Kenya. JAIDS. 2014;67(4):446–53.PubMedGoogle Scholar
  53. 53.
    Francis JM, Helander A, Kapiga SH, Weiss HA, Grosskurth H. Validation of the MINI (DSM IV) tool for the assessment of alcohol dependence among young people in northern Tanzania using the alcohol biomarker phosphatidylethanol (PEth). Int J Environ Res Public Health. 2015;12(11):14021–33.CrossRefPubMedPubMedCentralGoogle Scholar
  54. 54.
    Francis JM, Weiss HA, Helander A, Kapiga SH, Changalucha J, Grosskurth H. Comparison of self-reported alcohol use with the alcohol biomarker phosphatidylethanol among young people in northern Tanzania. Drug. 2015;156:289–96.Google Scholar
  55. 55.
    Schröck A, Wurst FM, Thon N, Weinmann W. Assessing phosphatidylethanol (PEth) levels reflecting different drinking habits in comparison to the alcohol use disorders identification test–C (AUDIT-C). Drug. 2017;178:80–6.Google Scholar
  56. 56.
    Gnann H, Weinmann W, Thierauf A. Formation of phosphatidylethanol and its subsequent elimination during an extensive drinking experiment over 5 days. Alcohol Clin Exp Res. 2012;36(9):1507–11.CrossRefPubMedGoogle Scholar
  57. 57.
    Lee K, Hutton HE, Lesko CR, et al. Associations of drug use, violence, and depressive symptoms with sexual risk behaviours among women with alcohol misuse. Womens Health Issues. 2018;S1049–3867(17):30482–6.Google Scholar
  58. 58.
    Kebede D, Fekadu A, Alem A, Beyero T, Shibire T, Deyessa N. The distribution of mental disorders among an isolated island community in southern Ethiopia. EMJ. 2005;43(2):71–7.PubMedGoogle Scholar
  59. 59.
    Sileo KM, Kiene SM. History of sexual abuse, depression, and alcohol use as risk factors for HIV infection in high HIV prevalence fishing communities in rural Uganda. Ann Glob Health. 2015;81(1):134–5.CrossRefGoogle Scholar
  60. 60.
    Tumwesigye NM, Atuyambe L, Wanyenze RK, et al. Alcohol consumption and risky sexual behaviour in the fishing communities: evidence from two fish landing sites on Lake Victoria in Uganda. BMC Public Health. 2012;12:1069.CrossRefPubMedPubMedCentralGoogle Scholar
  61. 61.
    Bing EG, Ortiz DJ, Ovalle-Bahamon RE, et al. HIV/AIDS behavioral surveillance among Angolan military men. AIDS Behav. 2008;12(4):578–84.CrossRefPubMedGoogle Scholar
  62. 62.
    Cheng GK, Ortiz DJ, Weiss RE, et al. Patterns of alcohol consumption and factors influencing problematic drinking among Angolan soldiers. J Subst Abus Alcohol. 2012;17(2):138–49.Google Scholar
  63. 63.
    Courtney LP, Goco N, Woja J, Farris T, et al. HIV prevalence and behavioral risk factors in the Sudan People’s Liberation Army: data from South Sudan. PLoS ONE. 2017;12(11):e0187689.CrossRefPubMedPubMedCentralGoogle Scholar
  64. 64.
    Djibo AM-D. Communicable diseases and gender norms in the Sierra Leone Armed Forces. Diss Abstr Int Sect B Sci Eng. 2016;76(9-B(E)). https://cloudfront.escholarship.org/dist/prd/content/qt5vq9k5ht/qt5vq9k5ht.pdf. Accessed 1 Dec 2016.
  65. 65.
    Sero Harbertson J. Prevalence and risk factors for human immunodeficiency virus in the Rwanda defense forces. Diss Abstr Int Sect B Sci Eng. 2011;71(8-B):4734.Google Scholar
  66. 66.
    Ijomanta IN, Olufolahan VL. Lifetime and 12 months prevalence of alcohol use and alcohol use disorders among soldiers residing in a military community in Ibadan. Subst Use Misuse. 2016;51(6):722–32.CrossRefPubMedGoogle Scholar
  67. 67.
    Ovuga E, Madrama C. Burden of alcohol use in the Uganda Police in Kampala District. Afr Health Sci. 2006;6(1):14–20.PubMedPubMedCentralGoogle Scholar
  68. 68.
    Tran BR, Thomas AG, Ditsela M, et al. Condom use behaviours and correlates of use in the Botswana Defence Force. Int J STD AIDS. 2013;24(11):883–92.CrossRefPubMedPubMedCentralGoogle Scholar
  69. 69.
    Bello S, Fatiregun A, Oyo-Ita A, Ikpeme B. Dose-response relationship between alcohol use and blood pressure among drivers of commercial vehicles in Calabar, southern Nigeria. J Public Health Epidemiol. 2010;1(1):17–9.Google Scholar
  70. 70.
    Botão C, Horth RZ, Frank H, Cummings B, et al. Prevalence of HIV and associated risk factors among long distance truck drivers in Inchope, Mozambique, 2012. AIDS Behav. 2016;20(4):811–20.CrossRefPubMedPubMedCentralGoogle Scholar
  71. 71.
    Tumwesigye NM, Atuyambe LM, Kobusingye OK. Factors associated with injuries among commercial motorcyclists: evidence from a matched case control study in Kampala City, Uganda. PLoS ONE. 2016;11(2):e0148511.CrossRefPubMedPubMedCentralGoogle Scholar
  72. 72.
    Alem A, Kebede D, Mitike G, Lemma W. Unprotected sex, sexually transmitted infections and problem drinking among female sex workers in Ethiopia. Ethiop J Health Dev. 2006;20(2):93–8.Google Scholar
  73. 73.
    Augusto Âdo R, Young PW, Horth RZ, et al. High burden of HIV infection and risk behaviors among female sex workers in three main urban areas of Mozambique. AIDS and Behav. 2016;20(4):799–810.CrossRefGoogle Scholar
  74. 74.
    Chersich MF, Luchters SM, Malonza IM, Mwarogo P, King’ola N, Temmerman M. Heavy episodic drinking among Kenyan female sex workers is associated with unsafe sex, sexual violence and sexually transmitted infections. Int J STD AIDS. 2007;18(11):764–9.CrossRefPubMedGoogle Scholar
  75. 75.
    Lancaster KT, Mmodzi P, Hosseinipour MC, Chadwick K, Powers KA, Pence BW. The association between substance use and sub-optimal HIV treatment engagement among HIV-infected female sex workers in Lilongwe, Malawi. AIDS Care. 2017;29(2):197–203.Google Scholar
  76. 76.
    Gezie LD, Taye BW, Ayele TA. Time to unsafe sexual practice among cross-border female sex workers in Metemma Yohannes, North West Ethiopia. BMC Public Health. 2015;15:710.CrossRefPubMedPubMedCentralGoogle Scholar
  77. 77.
    Luchters S, Geibel S, Syengo M, et al. Use of AUDIT, and measures of drinking frequency and patterns to detect associations between alcohol and sexual behaviour in male sex workers in Kenya. BMC Public Health. 2011;11:384.CrossRefPubMedPubMedCentralGoogle Scholar
  78. 78.
    Magni S, Christofides N, Johnson S, Weiner R. Alcohol use and transactional sex among women in South Africa: results from a Nationally Representative Survey. PLoS ONE. 2015;10(12):e0145326.CrossRefPubMedPubMedCentralGoogle Scholar
  79. 79.
    Muraguri N, Tun W, Okal J, et al. HIV and STI prevalence and risk factors among male sex workers and other men who have sex with men in Nairobi, Kenya. JAIDS. 2015;68(1):91–6.PubMedGoogle Scholar
  80. 80.
    Mooney A, Kidanu A, Bradley HM, Kumoji EK, Kennedy CE, Kerrigan D. Work-related violence and inconsistent condom use with non-paying partners among female sex workers in Adama City, Ethiopia. BMC Public Health. 2013;13:771.CrossRefPubMedPubMedCentralGoogle Scholar
  81. 81.
    Nouaman MN, Meless DG, Coffie PA, et al. Oral health and HIV infection among female sex workers in Abidjan, Cote d’Ivoire. BMC Oral Health. 2015;15:154.CrossRefPubMedPubMedCentralGoogle Scholar
  82. 82.
    Odukoya OO, Sekoni AO, Onajole AT, Upadhyay RP. Alcohol consumption and cigarette smoking pattern among brothel-based female sex workers in two local government areas in Lagos state, Nigeria. Afr Health Sci. 2013;13(2):490–7.PubMedPubMedCentralGoogle Scholar
  83. 83.
    Richter ML, Chersich M, Temmerman M, Luchters S. Characteristics, sexual behaviour and risk factors of female, male and transgender sex workers in South Africa. S Afr Med J. 2013;103(4):246–51.CrossRefPubMedGoogle Scholar
  84. 84.
    Wilson KS, Deya R, Masese L, et al. Prevalence and correlates of intimate partner violence in HIV-positive women engaged in transactional sex in Mombasa, Kenya. Int J STD AIDS. 2016;27(13):1194–203.CrossRefPubMedGoogle Scholar
  85. 85.
    Buchanan DJ. Studies on blood alcohol in the workers of a Zambian copper mine. Alcohol Alcohol. 1988;23(3):239–42.PubMedGoogle Scholar
  86. 86.
    Gunga HC, Forson K, Amegby N, Kirsch K. Living conditions and state of health of miners and factory workers in the tropical rain forest of Ghana. [German]. Arbeitsmedizin Sozialmedizin Praventivmedizin. 1991;26(1):17-8+23-5.Google Scholar
  87. 87.
    Lewis JJ, Fielding KL, Grant AD, Chihota VN, Popane F, Luttig M, Muller D, Coetzee L, Churchyard GJ. Eligibility for isoniazid preventive therapy in South African gold mines. PLoS ONE. 2013;8(11):e81376.CrossRefPubMedPubMedCentralGoogle Scholar
  88. 88.
    Kiwanuka N, Ssetaala A, Mpendo J, et al. High HIV-1 prevalence, risk behaviours, and willingness to participate in HIV vaccine trials in fishing communities on Lake Victoria, Uganda. J Int AIDS Soc. 2013;16:8.CrossRefGoogle Scholar
  89. 89.
    Seeley J, Nakiyingi-Miiro J, Kamali A, et al. High HIV incidence and socio-behavioral risk patterns in fishing communities on the shores of Lake Victoria, Uganda. Sex Transm Infect. 2012;39(6):433–9.CrossRefGoogle Scholar
  90. 90.
    Essien EJ, Ogungbade GO, Ward D, et al. Influence of educational status and other variables on human immunodeficiency virus risk perception among military personnel: a large cohort finding. Mill Med. 2007;172(11):1177–81.CrossRefGoogle Scholar
  91. 91.
    Mion G, Oberti M. Epidemiological study of qat [khat] use in the National Army of Djibouti. Med Trop. 1998;58(2):161–4.Google Scholar
  92. 92.
    Odenwald M, Hinkel H, Schauer E, Schauer M, Elbert T, Neuner F, Rockstroh B. Use of khat and posttraumatic stress disorder as risk factors for psychotic symptoms: a study of Somali combatants. Soc Sci Med. 2009;69(7):1040–8.CrossRefPubMedGoogle Scholar
  93. 93.
    Argaw R, Seyoum B, Egata G. Influencing preventive behavior with regard to HIV/AIDS among the Police Force of Harari Region, Eastern Ethiopia, 2011. Ethiop J Health Dev. 2012;26(1):3–8.Google Scholar
  94. 94.
    Okulate GT, Jones OB, Olorunda MB. Condom use and other HIV risk issues among Nigerian soldiers: challenges for identifying peer educators. AIDS Care. 2008;20(8):911–6.CrossRefPubMedGoogle Scholar
  95. 95.
    Adejugbagbe AM, Fatiregun AA, Rukewe A, Alonge T. Epidemiology of road traffic crashes among long distance drivers in Ibadan, Nigeria. Afr Health Sci. 2015;15(2):480–8.CrossRefPubMedPubMedCentralGoogle Scholar
  96. 96.
    Adjei AA, Atta PB, Krampa F, et al. Human immunodeficiency virus, hepatitis B virus and syphilis infections among long-distance truck drivers in, a Port city in Ghana. Afr J Infect Dis. 2016;10(1):10–6.Google Scholar
  97. 97.
    Okpataku CI. Sociodemographic correlates of substance use among long distance commercial vehicle drivers. J Trop Med. 2016;18(1):6–11.CrossRefGoogle Scholar
  98. 98.
    Alemayehu M, Yohannes G, Damte A, et al. Prevalence and predictors of sexual violence among commercial sex workers in Northern Ethiopia. Reprod Health. 2015;12(1):47.CrossRefPubMedPubMedCentralGoogle Scholar
  99. 99.
    Cheuk E, Gichangi P, Blanchard J et al. Substance use and experience of violence among young women engaged in casual, transactional, and formal sex work in Mombasa, Kenya. Sexually Transmitted Diseases; 2016; Philadelphia, PA 19103 USA.: Lippincott Williams & Wilkins.Google Scholar
  100. 100.
    Decker MR, Lyons C, Billong SC, et al. Gender-based violence against female sex workers in Cameroon: prevalence and associations with sexual HIV risk and access to health services and justice. Sex Transm Infect. 2016;92(8):599–604.CrossRefPubMedGoogle Scholar
  101. 101.
    Hladik W, Baughman AL, Serwadda D, et al. Burden and characteristics of HIV infection among female sex workers in Kampala, Uganda—a respondent-driven sampling survey. BMC Public Health. 2017;17(1):565.CrossRefPubMedPubMedCentralGoogle Scholar
  102. 102.
    Kerrigan D, Mbwambo J, Likindikoki S, et al. Project Shikamana: baseline findings from a community empowerment-based combination HIV prevention trial among female sex workers in Iringa, Tanzania. J Acquir Immune Defic Syndr. 2017;74(Suppl 1):S60.CrossRefPubMedGoogle Scholar
  103. 103.
    Niama FR, Bongolo NCL, Mayengue PI, et al. A study on HIV, Syphilis, and Hepatitis B and C virus infections among female sex workers in the Republic of Congo. Arch Public Health. 2017;75(1):21.CrossRefPubMedPubMedCentralGoogle Scholar
  104. 104.
    Bukenya J, Vandepitte J, Kwikiriza M, Weiss HA, Hayes R, Grosskurth H. Condom use among female sex workers in Uganda. AIDS Care. 2013;25(6):767–74.CrossRefPubMedGoogle Scholar
  105. 105.
    Abaasa AA, Price MA, Ruzagira E, et al. Comparison of HIV incidence estimated in clinical trial and observational cohort settings in a high risk fishing population in Uganda: implications for sample size estimates. Vaccine. 2016;34(15):1778–85.CrossRefPubMedPubMedCentralGoogle Scholar
  106. 106.
    Bugssa G, Dessalegn B, Dimtsu B, Berhane Y. Prevalence and factors associated with HIV and hepatitis B virus infections among female commercial sex workers in mekelle, Ethiopia: cross sectional study. Int J Pharm Sci Res. 2015;6(1):135–46.Google Scholar
  107. 107.
    Fawole OI, Dagunduro AT. Prevalence and correlates of violence against female sex workers in Abuja, Nigeria. Afr Health Sci. 2014;14(2):299–313.CrossRefPubMedPubMedCentralGoogle Scholar
  108. 108.
    Fonck K, Kaul R, Kimani J, et al. A randomized, placebo-controlled trial of monthly azithromycin prophylaxis to prevent sexually transmitted infections and HIV-1 in Kenyan sex workers: study design and baseline findings. Int J STD AIDS. 2000;11(12):804–11.CrossRefPubMedGoogle Scholar
  109. 109.
    González-Guarda RM, McCabe BE, Florom-Smith A, Cianelli R, Peragallo N. Substance abuse, violence, HIV, and depression: an underlying syndemic factor among Latinas. Nurs Res. 2011;60:182.CrossRefPubMedPubMedCentralGoogle Scholar
  110. 110.
    Kayembe PKM, Busangu MA, Nyandwe AF, et al. Determinants of consistent condom use among female commercial sex workers in the Democratic Republic of Congo: implications for interventions. Sex Transm Infect. 2008;84(3):202–6.CrossRefPubMedGoogle Scholar
  111. 111.
    Lancaster KE, Go VF, Lungu T, et al. Substance use and HIV infection awareness among HIV-infected female sex workers in Lilongwe, Malawi. Int J Drug Policy. 2016;30:124–31.CrossRefPubMedPubMedCentralGoogle Scholar
  112. 112.
    Longo JDD, Simaléko MM, Ngbale R, Grésenguet G, Brücker G, Bélec L. Spectrum of female commercial sex work in Bangui, Central African Republic. SAHARA J. 2017;14(1):171–84.CrossRefPubMedPubMedCentralGoogle Scholar
  113. 113.
    McKinnon LRG, Juno GJ, AIzulla A, et al. High HIV risk in a cohort of male sex workers from Nairobi, Kenya. Sex Transm Infect. 2014;90(3):237–42.CrossRefPubMedGoogle Scholar
  114. 114.
    Micheni MR, Wahome S, Darwinkel E, et al. Risk of sexual, physical and verbal assaults on men who have sex with men and female sex workers in coastal Kenya (Special Issue: HIV epidemic in MSM in Kenya). AIDS. 2015;29(Suppl. 3):S231–6.CrossRefPubMedPubMedCentralGoogle Scholar
  115. 115.
    Cheuk E, Mishra S, Gichangi P, Blanchard J, Aral S, Musyoki H, et al., editors. Substance use and experience of violence among young women engaged in casual, transactional, and formal sex work in Mombasa, Kenya. Sexually transmitted diseases; 2016: Lippincott Williams & Wilkins, Philadelphia, PA, USA.Google Scholar
  116. 116.
    Okafor UO, Crutzen R, Ifeanyi O, Adebajo S, Borne H. HIV prevalence and high-risk behaviour of young brothel and non-brothel based female sex workers in Nigeria. BMC Res Notes. 2017;10(1):380.CrossRefPubMedPubMedCentralGoogle Scholar
  117. 117.
    Peltzer K. Stress, psychological symptoms, social support and health behaviour among black students in South Africa. J Child Adolesc Ment Health. 2004;16:19–23.CrossRefPubMedGoogle Scholar
  118. 118.
    Weldegebreal R, Melaku YA, Alemayehu M, Gebrehiwot TG. Unintended pregnancy among female sex workers in Mekelle city, northern Ethiopia: a cross-sectional study. BMC Public Health. 2015;15:40.CrossRefPubMedPubMedCentralGoogle Scholar
  119. 119.
    Tegang SP. Concurrent sexual and substance-use risk behaviours among female sex workers in Kenya’s Coast Province: findings from a behavioural monitoring survey. SAHARA J. 2010;7(4):10–6.CrossRefPubMedGoogle Scholar
  120. 120.
    Van der Elst EM, Okuku HS, Nakamya P, Muhaari A, Davies A, McClelland RS, et al. Is audio computer-assisted self-interview (ACASI) useful in risk behaviour assessment of female and male sex workers, Mombasa, Kenya? PLoS ONE. 2009;4(5):e5340.CrossRefPubMedPubMedCentralGoogle Scholar
  121. 121.
    Vandenhoudt HM, Langat L, Menten J, et al. Prevalence of HIV and other sexually transmitted infections among female sex workers in Kisumu, Western Kenya, 1997 and 2008. PLoS ONE. 2013;8(1):e54953.CrossRefPubMedPubMedCentralGoogle Scholar
  122. 122.
    Wilson KS, Odem-Davis K, Shafi J, et al. Association between alcohol use and sexually transmitted infection incidence among kenyan women engaged in transactional sex. AIDS Behav. 2014;18(7):1324–9.CrossRefPubMedPubMedCentralGoogle Scholar
  123. 123.
    Tadesse T, Kebede Z, Tamirayehu T. Assessment of substance abuse and risky sexual behaviour among female sex workers in Addis-ketema sub city, Addis-Ababa, Ethiopia. J Public Health Epidemiol. 2016;8(9):158–68.Google Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.MRC/UVRI and LSHTM Uganda Research UnitEntebbeUganda
  2. 2.Department of Infectious Disease EpidemiologyLondon School of Hygiene and Tropical MedicineLondonUK
  3. 3.Department of Global Health and DevelopmentLondon School of Hygiene and Tropical MedicineLondonUK
  4. 4.MRC Tropical Epidemiology GroupLondon School of Hygiene and Tropical MedicineLondonUK
  5. 5.Department of Non-Communicable Disease EpidemiologyLondon School of Hygiene and Tropical MedicineLondonUK
  6. 6.International AIDS Vaccine Initiative (IAVI)NairobiKenya

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