Composite Risk for HIV: A New Approach Towards Integrating Biomedical and Behavioral Strategies in Couples-Based HIV Prevention Research
- 533 Downloads
A substantial number of new HIV infections among gay, bisexual, and other men who have sex with men and transgender women occurs in the context of primary partnerships. Given the diversity of risk reduction needs and various approaches available for reducing risk within couples, condomless sex is no longer the gold standard HIV outcome. We present a novel, comprehensive, and flexible Composite Risk for HIV (CR-HIV) approach for integrating evolving biomedical and behavioral HIV prevention strategies into couples-based HIV prevention intervention and survey research. We provide illustrative examples of the utility of the CR-HIV approach based on couples’ HIV status.
KeywordsCouples HIV prevention Men who have sex with men Transgender women
The authors thank both Dr. Gregory Greenwood and Dr. Susannah Allison for their support.
Funding was provided by National Institute of Mental Health (Grant No. R01MH110289; Grant No. R01MH115765). The first author was also supported by research education grant (Grant No. R25MH067127). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Compliance with Ethical Standards
Conflict of interest
Each of the authors declare that they have no conflict of interest.
- 1.Centers for Disease Control and Prevention. CDC Fact Sheet: HIV among gay and bisexual men. 2018.Google Scholar
- 15.Operario D, Gamarel KE, Iwamoto M, Suzuki S, Suico S, Dabes LA, et al. Couples-focused prevention program to reduce HIV risk among transgender women and their primary male partners: feasibility and promise of the Couples HIV Intervention Program. AIDS Behav. 2017;21(8):2452–63.PubMedPubMedCentralCrossRefGoogle Scholar
- 18.Yaylali E, Farnham P, Jacobson E, Allaire BT, Wagner DL, Hicks KA, et al. Impact of improving HIV care and treatment and initiating PrEP in the United States, 2015–2020. In: Conference on Retroviruses and Opportunistic Infections. Boston, MA; 2016.Google Scholar
- 20.Centers for Disease Control and Prevention. Evidence of HIV treatment and viral suppression in preventing the sexual transmission of HIV. 2017.Google Scholar
- 21.Malone J, Syverston JL, Johnson BE, Mimiaga MJ, Mayer KH, Bazzi AR. Negotiating sexual safety in the era of biomedical HIV prevention: relationship dynamics among male couples using pre-exposure prophylaxis. Cult Health Sex. 2017;375:1–15.Google Scholar
- 23.Meyers K, Golub SA. Planning ahead for implementation of long acting HIV prevention: challenges and opportunities. Curr HIV/AIDS Rep. 2015;10(4):290–5.Google Scholar
- 27.Joint UN Programme on HIV/AIDS (UNAIDS). 90-90-90 An ambitious treatment target to help end the AIDS epidemic. In. Geneva, Switzerland; 2014.Google Scholar
- 38.Baeten JM, Heffron R, Kidoguchi L, et al. Integrated delivery of PrEP and ART results in sustained near elimination of HIV transmission in African HIV serodiscordant couples: Final results from the Partners Demonstration Project. In: JIAS 2016.Google Scholar
- 39.World Health Organization. Guidance on couples HIV testing and counselling, including antiretroviral therapy for treatment and prevention in serodiscordant couples. Geneva: World Health Organization; 2012.Google Scholar
- 44.Mitchell JW, Petroll AE. HIV testing rates and factors associated with recent HIV testing among male couples. Sex Trans Dis. 2012;39(12):1–3.Google Scholar
- 51.Mimiaga MJ, Closson EF, Kothary V, Mitty JA. Sexual partnerships and considerations for HIV antiretroviral pre-exposure prophylaxis utilization among high-risk substance using men who have sex with men. Arch Sex Behav. 2013;43:1–8.Google Scholar