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AIDS and Behavior

, Volume 23, Issue 2, pp 313–317 | Cite as

Comparisons of New HIV Rapid Test Kit Performance

  • Dennis G. FisherEmail author
  • Kristen L. Hess
  • Grace L. Reynolds
  • Todd A. Alonzo
  • Loucine M. Huckabay
  • Lucy Van Otterloo
  • David W. Hosmer
Original Paper
  • 85 Downloads

Abstract

The development of rapid point-of-care tests for HIV infection has greatly reduced the problem of failure to return for test results. Test manufacturers are now developing test kits that can test for two or even three diseases at the same time, multiple-disease test kits. This study reports on the sensitivity and specificity of HIV tests when included on multi-disease test kits. 1029 participants were recruited from 2011 to 2014. HIV test kit sensitivities ranged from 91.1 to 100%, and the HIV test kit specificities from 99.5 to 100%. The two HIV kits which used oral fluid instead of blood performed well.

Keywords

HIV testing Point-of-care tests Rapid tests 

Resumen

El desarrollo de pruebas rápidas en el punto de atención (POC) para la infección del VIH ha reducido enormemente el problema de la falta de retorno por los resultados de las pruebas por parte del paciente. Los fabricantes de pruebas ya están desarrollando kits que pueden probar dos o incluso tres enfermedades al mismo tiempo, los llamados kits de prueba de enfermedades múltiples. Este estudio informa sobre la sensibilidad y especificidad de las pruebas de VIH cuando se incluyen en kits de pruebas de enfermedades múltiples. 1029 participantes fueron reclutados entre 2011 y 2014. Las sensibilidades del kit de prueba de VIH oscilaron entre 91.1% y 100%, en tanto que las especificidades estuvieron entre 99.5% y 100%. Los dos kits de VIH que usan fluido oral en lugar de sangre funcionaron bien.

Notes

Acknowledgements

The project described was supported in part by Award Numbers R01DA030234 from the National Institute on Drug Abuse (NIDA), P20MD003942 from the National Institute of Minority Health and Health Disparities (NIMHD), ID10-CSULB-008 from the California HIV Research Program (CHRP). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute on Drug Abuse, the National Institute of Minority Health and Health Disparities, the National Institutes of Health, or the California HIV Research Program. The NIDA, NIMHD, and CHRP had no role in the study design, collection, analysis or interpretation of the data, writing of the manuscript, or the decision to submit the paper for publication.

Compliance with Ethical Standards

Conflicts of interest

All authors declare that they have no conflicts of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study under a protocol and using an Informed Consent Form approved by the California State University, Long Beach, Institutional Review Board.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Center for Behavioral Research and ServicesCalifornia State University, Long BeachLong BeachUSA
  2. 2.Department of PsychologyCalifornia State University, Long BeachLong BeachUSA
  3. 3.Children’s Oncology Group, Department of Preventive MedicineUniversity of Southern CaliforniaMonroviaUSA
  4. 4.School of NursingCalifornia State University, Long BeachLong BeachUSA
  5. 5.Department of Mathematics and StatisticsUniversity of VermontStoweUSA

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