AIDS and Behavior

, Volume 22, Issue 3, pp 701–710 | Cite as

HIV Linkage to Care and Retention in Care Rate Among MSM in Guangzhou, China

  • Ngai Sze Wong
  • Jessica Mao
  • Weibin Cheng
  • Weiming Tang
  • Myron S. Cohen
  • Joseph D. Tucker
  • Huifang XuEmail author
Original Paper


Quantifying HIV service provision along the HIV care continuum is increasingly important for monitoring and evaluating HIV interventions. We examined factors associated with linkage and retention in care longitudinally among MSM (n = 1974, 4933 person-years) diagnosed and living in Guangzhou, China, in 2008–2014. We measured longitudinal change of retention in care (≥2 CD4 tests per year) from linkage and antiretroviral therapy initiation (ART). We examined factors associated with linkage using logistic regression and with retention using generalized estimating equations. The rate of linkage to care was 89% in 2014. ART retention rate dropped from 71% (year 1) to 46% (year 2), suggesting that first-year retention measures likely overestimate retention over longer periods. Lower CD4 levels and older age predicted retention in ART care. These data can inform interventions to improve retention about some subgroups.


HIV care continuum Linkage to care Retention in care China MSM 



The authors thank all staff of Guangzhou Center for Disease Control and Prevention for their assistance in the maintenance of the database used in this study. Li Ka Shing Institute of Health Sciences and Stanley Ho Centre for Emerging Infectious Diseases of The Chinese University of Hong Kong are acknowledged for providing technical support in conducting the research.


The authors disclosed receipt of the following financial support for the research, authorship and/or publication of this article: This research was funded by The Project for Key Medicine Discipline Construction of Guangzhou Municipality (Grant Number 2017-2019-07), Bill & Melinda Gates Foundation to the MeSH Consortium (BMGF-OPP1120138), NIH Fogarty International Center Grant, the South China-UNC STD Research Training Center Grant (FIC1D43TW009532-01), SESH R01 Grant (NIAID 1R01AI114310), and Doris Duke International Clinical Research Grant.


The opinions and assertions contained herein are private views of the authors and do not necessarily reflect their affiliating institutions.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

IRB approval was obtained from the Guangzhou CDC, and the Guangdong Provincial Center for Skin Diseases and STI Control, China, and from University of North Carolina at Chapel Hill.


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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  • Ngai Sze Wong
    • 1
    • 2
    • 3
  • Jessica Mao
    • 4
  • Weibin Cheng
    • 5
  • Weiming Tang
    • 1
    • 2
  • Myron S. Cohen
    • 1
  • Joseph D. Tucker
    • 1
    • 2
  • Huifang Xu
    • 5
    Email author
  1. 1.Institute for Global Health & Infectious DiseasesUniversity of North Carolina at Chapel HillChapel HillUSA
  2. 2.University of North Carolina Project-ChinaGuangzhouChina
  3. 3.Stanley Ho Centre for Emerging Infectious DiseasesThe Chinese University of Hong KongHong KongChina
  4. 4.David Geffen School of MedicineUniversity of CaliforniaLos AngelesUSA
  5. 5.Department of AIDS/STD Control and PreventionGuangzhou Center for Disease Control and PreventionGuangzhouChina

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