HPTN 068: A Randomized Control Trial of a Conditional Cash Transfer to Reduce HIV Infection in Young Women in South Africa—Study Design and Baseline Results
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Young women in South Africa are at high risk for HIV infection. Cash transfers offer promise to reduce HIV risk. We present the design and baseline results from HPTN 068, a phase III, individually randomized trial to assess the effect of a conditional cash transfer on HIV acquisition among South African young women. A total of 2533 young women were randomized to receive a monthly cash transfer conditional on school attendance or to a control group. A number of individual-, partner-, household- and school-level factors were associated with HIV and HSV-2 infection. After adjusting for age, all levels were associated with an increased odds of HIV infection with partner-level factors conveying the strongest association (aOR 3.05 95 % CI 1.84–5.06). Interventions like cash transfers that address structural factors such as schooling and poverty have the potential to reduce HIV risk in young women in South Africa.
KeywordsHIV Adolescents South Africa Young women HIV prevention Cash transfers Education
Overall support for the HIV Prevention Trials Network (HPTN) was provided by the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Mental Health (NIMH) and the National Institute on Drug Abuse (NIDA) of the National Institutes of Health (NIH) under Award Numbers UM1AI068619 (HPTN Leadership and Operations Center), UM1AI068617 (HPTN Statistical and Data Management Center), and UM1AI068613 (HPTN Laboratory Center). The study was also funded under Award Number 5R01MH087118-02 and R24 HD050924 to the Carolina Population Center. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Allergy and Infectious Diseases or the National Institutes of Health.
- 1.Shisana O, Rehle T, LC S, Zuma K, Jooste S, N Z, et al. South African National HIV prevalence, incidence and behaviour survey 2012. Cape Town; 2014.Google Scholar
- 2.Abdool Karim Q, Kharsany AB, Frohlich JA, Werner L, Mashego M, Mlotshwa M, et al. Stabilizing HIV prevalence masks high HIV incidence rates amongst rural and urban women in KwaZulu-Natal, South Africa. Int J Epidemiol. 2010.Google Scholar
- 4.UNAIDS. The gap report. Geneva: UNAIDS; 2014.Google Scholar
- 10.Fizbein A, Schady N. Conditional cash transfers reducing present and future poverty. 2009.Google Scholar
- 19.García-Moreno C, et al. WHO multi-country study on women’s health and domestic violence against women: initial results on prevalence, health outcomes and women’s responses. Geneva; 2005.Google Scholar
- 21.UNICEF. Social protection preogrammes contribute to HIV prevention. 2015.Google Scholar
- 23.Department of Social Development, SASSA, UNICEF. The South African Child Support Grant impact assessment: evidence from a survey of children, adolescents, and their households. Pretoria; 2012.Google Scholar
- 24.Pettifor A, Rees H, Steffenson A, Hlongwa-Madikizela L, MacPhail C, Vermaak K, et al. HIV and sexual behaviour among young South African a national survey of 15–24 year olds. Johannesburg: Reproductive Health Research Unit; 2004.Google Scholar