AIDS and Behavior

, Volume 19, Issue 5, pp 752–757 | Cite as

Acceptability of HIV Pre-exposure Prophylaxis (PrEP) Among People Who Inject Drugs (PWID) in a Canadian Setting

  • Daniel J. Escudero
  • Thomas Kerr
  • Evan Wood
  • Paul Nguyen
  • Mark N. Lurie
  • Omar Sued
  • Brandon D. L. Marshall
Brief Report

Abstract

A recent clinical trial provided evidence that pre-exposure prophylaxis (PrEP) has the potential to prevent HIV infection among people who inject drugs (PWID). We examined willingness to use PrEP among HIV-negative PWID in Vancouver, Canada (n = 543) to inform PrEP implementation efforts. One third (35.4 %) expressed willingness to use PrEP, with adjusted models indicating that younger age, no regular employment, requiring help injecting, engaging in sex work, and reporting multiple recent sexual partners were positively associated with willingness to use PrEP. Although willingness to use PrEP was low, PrEP was acceptable to some PWID at heightened risk for HIV infection.

Keywords

PrEP PWID Acceptability HIV Risk behavior 

Resumen

Reciente se demostró que la profilaxis pre-exposición (PrEP) puede evitar la infección por VIH entre personas que se inyectan drogas por vía intravenosa (PWID). Examinamos la predisposición a utilizar PrEP entre PWID HIV negativos en Vancouver, Canadá. La tercera parte (35.4 %) estaban dispuestos a usar PrEP. En el análisis ajustado menor edad, falta de empleo estable, requerir ayuda para inyectarse, trabajado sexual y haber tenido múltiples parejas sexuales recientemente se asociaron de manera positiva a utilizar PrEP. Aunque la predisposición global a utilizar PrEP fue baja, fue aceptable para algunas PWID a mayor riesgo para la infección por el VIH.

Notes

Acknowledgments

The study was supported by the US National Institutes of Health (R01DA011591). Thomas Kerr is supported by the Michael Smith Foundation for Health Research and the Canadian Institutes of Health Research. Mark Lurie received partial support from the NIH through two research Grants (1R01MH083539-01 and 1R24HD077976-01). Daniel Escudero is supported by an NIH Grant (F31-DA037808). We would also like to thank Dr. Kenneth Mayer for his assistance with developing the survey instrument.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Daniel J. Escudero
    • 1
  • Thomas Kerr
    • 2
    • 3
  • Evan Wood
    • 2
    • 3
  • Paul Nguyen
    • 2
  • Mark N. Lurie
    • 1
  • Omar Sued
    • 4
  • Brandon D. L. Marshall
    • 1
  1. 1.Department of Epidemiology, School of Public HealthBrown UniversityProvidenceUSA
  2. 2.British Columbia Centre for Excellence in HIV/AIDSSt. Paul’s HospitalVancouverCanada
  3. 3.Department of MedicineUniversity of British ColumbiaVancouverCanada
  4. 4.Fundación HuéspedBuenos AiresArgentina

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