AIDS and Behavior

, Volume 18, Issue 10, pp 1864–1887

Systematic Review of Couple-Based HIV Intervention and Prevention Studies: Advantages, Gaps, and Future Directions

Substantive Review

DOI: 10.1007/s10461-014-0827-7

Cite this article as:
Jiwatram-Negrón, T. & El-Bassel, N. AIDS Behav (2014) 18: 1864. doi:10.1007/s10461-014-0827-7


We conducted a systematic review of couple-based HIV biobehavioral (skills-building, VCT, and adherence) and biomedical (ART, circumcision) prevention and intervention studies designed to reduce sexual- and drug-risk behaviors and HIV transmission and acquisition. Of the 11,162 papers identified in the search, 93 peer-reviewed papers met the inclusion criteria and yielded a total of 33 studies conducted globally. Biobehavioral couple-based prevention and intervention studies have been efficacious in reducing sexual- and drug-risk behaviors, increasing access to HIV testing and care, and improving adherence. Biomedical couple-based studies were found to reduce HIV incidence among HIV-negative sex partners and viral load among HIV-positive partners. Despite much progress, couple-based HIV prevention and intervention studies remain limited; a number of methodological gaps exist and studies focusing on MSM, people who inject drugs, and sex workers are scarce.


Systematic review Couple-based HIV Prevention Intervention 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.School of Social WorkColumbia UniversityNew York CityUSA

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