Knowledge of Pre-exposure Prophylaxis (PrEP) for HIV Prevention Among Men Who Have Sex with Men in Denver, Colorado
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As part of the National HIV Behavioral Surveillance System among men who have sex with men (MSM) in Denver, Colorado, we assessed knowledge of pre-exposure prophylaxis (PrEP); willingness to use PrEP; and potential changes in risk behaviors among HIV-negative participants reporting sexual activity with a male partner in the preceding 12 months. We examined knowledge of PrEP before (2008) and after (2011) results of the iPrEx trial were available. Of the 425 participants in the 2008 sample, 91 (21 %) were aware of PrEP compared to 131 (28 %) of the 461 participants in the 2011 sample (adjusted prevalence ratio: 1.43, 95 % confidence interval: 1.18, 1.72). Despite the increase in 2011, few MSM in Denver were aware of PrEP. Educating high-risk MSM about the potential utility of PrEP as an adjunct to other effective prevention methods is needed when considering the addition of PrEP to the HIV prevention arsenal.
KeywordsBehavioral surveillance Men who have sex with men Pre-exposure prophylaxis
This work was supported in part by the Centers for Disease Control and Prevention (U62-PS000954). Data collection was based on CDC study protocols as part of the National HIV Behavioral Surveillance System. The authors gratefully acknowledge the contributions of Drs. Dawn Smith, Andrew Voetsch, Jeffrey Herbst, and James Carey to the PrEP questionnaire and to earlier presentations of this data. The authors are deeply indebted to Drs. Elizabeth DiNenno and Nevin Krishna for continued NHBS support during the development of this manuscript. The authors also thank Toby LeRoux, Charles Chen, Theresa Mickiewicz, and our Denver NHBS interviewers for their tireless efforts in collecting this important data and to the numerous NHBS participants who provided it.
- 11.U.S. Food and Drug Administration. FDA approves first drug for reducing risk of sexually acquired HIV infection. 2012 [cited 30 Oct 2012]. Available from: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm312210.htm.
- 12.CDC. Interim guidance: preexposure prophylaxis for the prevention of HIV infection in men who have sex with men. MMWR Morb Mortal Wkly Rep. 2011;60(03):65–8.Google Scholar
- 13.CDC. Interim guidance for clinicians considering the use of preexposure prophylaxis for the prevention of HIV infection in heterosexually active adults. MMWR Morb Mortal Wkly Rep. 2012;61(31):586–9.Google Scholar
- 14.CDC. Update to interim guidance for preexposure prophylaxis (PrEP) for the prevention of HIV infection: PrEP for injecting drug users. MMWR Morb Mortal Wkly Rep. 2013;62(23):463–5.Google Scholar
- 19.Mimiaga MJ, Case P, Johnson CV, Safren SA, Mayer KH. Preexposure antiretroviral prophylaxis attitudes in high-risk Boston area men who report having sex with men: limited knowledge and experience but potential for increased utilization after education. J Acquir Immune Defic Syndr. 2009;50(1):77–83.PubMedCentralPubMedCrossRefGoogle Scholar
- 24.Karon J. The analysis of time-location sampling data. American Statistical Association Section of Survey Research Methods 2005, Minneapolis; 2005. p. 3180–3186.Google Scholar
- 26.Galindo GR, Walker JJ, Hazelton P, Lane T, Steward WT, Morin SF, et al. Community member perspectives from transgender women and men who have sex with men on pre-exposure prophylaxis as an HIV prevention strategy: implications for implementation. Implement Sci. 2012;7:116.PubMedCentralPubMedCrossRefGoogle Scholar