AIDS and Behavior

, Volume 15, Issue 7, pp 1410–1415 | Cite as

Risk Factors for Medication Non-Adherence in an HIV Infected Population in the Dominican Republic

  • Julian Harris
  • Mara Pillinger
  • Deborah Fromstein
  • Bayardo Gomez
  • Ivelisse Garris
  • Peter A. Kanetsky
  • Pablo Tebas
  • Robert Gross
Original Paper


High levels of medication adherence are central to HIV treatment success. Barriers to medication adherence may differ by cultural setting. We aimed to determine risk factors for medication non-adherence in HIV infected individuals in the Dominican Republic. Adherence was measured in 300 individuals using a visual analog scale assessing the prior month and dichotomized at 95%. High levels of adherence were reported by 228 (76%). Risk factors for non-adherence included heavy alcohol use: 2.5 times odds (95% CI: 1.4–4.5), having children: 2.2 times higher odds (95% CI: 1.1–4.9) and perceptions of less social support related to adherence: 2 times higher odds (95% CI: 1.1–3.6). Culturally appropriate interventions are needed to address alcohol use, which is common in this setting. Parenting may represent a competing demand on time and resources and be an adherence barrier. Self-reported perceived lack of adherence support may be a useful marker for need for adherence interventions.


HIV-1 Antiretroviral therapy Adherence Developing world 


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Julian Harris
    • 1
  • Mara Pillinger
    • 2
  • Deborah Fromstein
    • 3
  • Bayardo Gomez
    • 4
  • Ivelisse Garris
    • 5
  • Peter A. Kanetsky
    • 6
  • Pablo Tebas
    • 7
    • 8
  • Robert Gross
    • 6
    • 7
    • 8
  1. 1.Department of Medicine (Resident)Brigham & Women’s Hospital, Harvard Medical SchoolBostonUSA
  2. 2.School of Arts and SciencesUniversity of PennsylvaniaPhiladelphiaUSA
  3. 3.Department of Medicine (Resident)University of WashingtonWashington, DCUSA
  4. 4.Health Promotion and Human Solidarity Center (CEPROSH)Puerto PlataDominican Republic
  5. 5.Galvan Health CenterSanto DomingoDominican Republic
  6. 6.Center for Clinical Epidemiology and BiostatisticsUniversity of Pennsylvania School of MedicinePhiladelphiaUSA
  7. 7.Department of Medicine (Infectious Diseases)University of Pennsylvania School of MedicinePhiladelphiaUSA
  8. 8.Center for AIDS Research (CFAR)University of PennsylvaniaPhiladelphiaUSA

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