AIDS and Behavior

, Volume 14, Issue 5, pp 1066–1071

Predicting Pregnancy in HIV-1-Discordant Couples

  • Brandon L. Guthrie
  • Robert Y. Choi
  • Rose Bosire
  • James N. Kiarie
  • Romel D. Mackelprang
  • Anne Gatuguta
  • Grace C. John-Stewart
  • Carey Farquhar
Report

DOI: 10.1007/s10461-010-9716-x

Cite this article as:
Guthrie, B.L., Choi, R.Y., Bosire, R. et al. AIDS Behav (2010) 14: 1066. doi:10.1007/s10461-010-9716-x

Abstract

This study examines the incidence and predictors of pregnancy in HIV-1-discordant couples from Nairobi, Kenya. Women from 454 discordant couples were followed for up to 2 years. One-year cumulative incidence of pregnancy was 9.7%. Pregnancy rates did not differ significantly between HIV-1-infected and uninfected women (HR = 1.46). The majority of pregnancies occurred among women < 30 years old reporting a desire for future children (1-year incidence 22.2%). Pregnancy rates may be high among discordant couples, indicating desire for children may override concerns of HIV-1 transmission and increase unprotected sex, and highlighting the need to make conception safer.

Keywords

HIV Discordant couples Serodiscordant Pregnancy Predictors Risk factor 

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Brandon L. Guthrie
    • 1
  • Robert Y. Choi
    • 2
  • Rose Bosire
    • 4
  • James N. Kiarie
    • 5
  • Romel D. Mackelprang
    • 1
  • Anne Gatuguta
    • 6
  • Grace C. John-Stewart
    • 1
    • 2
    • 3
  • Carey Farquhar
    • 1
    • 2
  1. 1.Department of EpidemiologyUniversity of WashingtonSeattleUSA
  2. 2.Department of MedicineUniversity of WashingtonSeattleUSA
  3. 3.Department of Global HealthUniversity of WashingtonSeattleUSA
  4. 4.Centre for Public Health ResearchKenya Medical Research InstituteNairobiKenya
  5. 5.Department of Obstetrics and GynaecologyUniversity of NairobiNairobiKenya
  6. 6.Department of Community HealthUniversity of NairobiNairobiKenya

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