AIDS and Behavior

, Volume 13, Supplement 1, pp 28–37

Antiretroviral Therapy is Associated with Increased Fertility Desire, but not Pregnancy or Live Birth, among HIV+ Women in an Early HIV Treatment Program in Rural Uganda

  • Marissa Maier
  • Irene Andia
  • Nneka Emenyonu
  • David Guzman
  • Angela Kaida
  • Larry Pepper
  • Robert Hogg
  • David R. Bangsberg
Original Paper

DOI: 10.1007/s10461-008-9371-7

Cite this article as:
Maier, M., Andia, I., Emenyonu, N. et al. AIDS Behav (2009) 13(Suppl 1): 28. doi:10.1007/s10461-008-9371-7

Abstract

To assess the association between antiretroviral therapy (ART) and fertility history and desire among HIV-positive Ugandan women, we conducted a cross-sectional study among HIV-positive Ugandan women aged 18–50 years who attended an HIV clinic at Mbarara University in western Uganda between November 1, 2005 and June 6, 2006. Of 538 women approached, 501 were enrolled. ART use was associated with increased odds of fertility desire (AOR 2.99, 95% CI 1.38–6.28), and decreased odds of pregnancy (AOR 0.56, 95% CI 0.33–0.95) and live birth (AOR 0.30, 95% CI 0.13–0.66). ART was associated with an increase in fertility desire, but was not associated with an increase in fertility. Additional studies will be needed to determine if this greater fertility desire among ART-treated women leads to an increase in fertility as ART use expands.

Keywords

Uganda Fertility HIV/AIDS Fertility desires Antiretroviral therapy 

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Marissa Maier
    • 1
  • Irene Andia
    • 3
  • Nneka Emenyonu
    • 2
  • David Guzman
    • 2
  • Angela Kaida
    • 4
    • 5
  • Larry Pepper
    • 3
  • Robert Hogg
    • 5
    • 6
  • David R. Bangsberg
    • 2
  1. 1.Department of Internal MedicineOregon Health & Science UniversityPortlandUSA
  2. 2.Department of Internal MedicineUniversity of California, San Francisco (UCSF)San FranciscoUSA
  3. 3.Department of Internal MedicineMbarara University of Science and TechnologyMbararaUganda
  4. 4.Department of Healthcare and Epidemiology, Faculty of MedicineUniversity of British Columbia (UBC)VancouverCanada
  5. 5.BC Centre for Excellence in HIV/AIDSVancouverCanada
  6. 6.Faculty of Health SciencesSimon Fraser UniversityBurnabyCanada

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