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Annals of Biomedical Engineering

, Volume 46, Issue 8, pp 1216–1227 | Cite as

Predictive Simulations of Neuromuscular Coordination and Joint-Contact Loading in Human Gait

  • Yi-Chung Lin
  • Jonathan P. Walter
  • Marcus G. Pandy
Article

ABSTRACT

We implemented direct collocation on a full-body neuromusculoskeletal model to calculate muscle forces, ground reaction forces and knee contact loading simultaneously for one cycle of human gait. A data-tracking collocation problem was solved for walking at the normal speed to establish the practicality of incorporating a 3D model of articular contact and a model of foot–ground interaction explicitly in a dynamic optimization simulation. The data-tracking solution then was used as an initial guess to solve predictive collocation problems, where novel patterns of movement were generated for walking at slow and fast speeds, independent of experimental data. The data-tracking solutions accurately reproduced joint motion, ground forces and knee contact loads measured for two total knee arthroplasty patients walking at their preferred speeds. RMS errors in joint kinematics were < 2.0° for rotations and < 0.3 cm for translations while errors in the model-computed ground-reaction and knee-contact forces were < 0.07 BW and < 0.4 BW, respectively. The predictive solutions were also consistent with joint kinematics, ground forces, knee contact loads and muscle activation patterns measured for slow and fast walking. The results demonstrate the feasibility of performing computationally-efficient, predictive, dynamic optimization simulations of movement using full-body, muscle-actuated models with realistic representations of joint function.

Keywords

Musculoskeletal model Dynamic optimization Collocation Knee contact model Foot–ground interaction 

Notes

Acknowledgments

This work was supported by a Discovery Projects Grant from the Australian Research Council (DP160104366).

Supplementary material

10439_2018_2026_MOESM1_ESM.pdf (368 kb)
Supplementary material 1 (PDF 369 kb)

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Copyright information

© Biomedical Engineering Society 2018

Authors and Affiliations

  1. 1.Department of Mechanical EngineeringUniversity of MelbourneParkvilleAustralia
  2. 2.CED TechnologiesJacksonvilleUSA

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