Design and Mechanical Properties of a Novel Cerebral Flow Diverter Stent
- 811 Downloads
Brain arterial aneurysms are localised dilatation in the wall of cerebral arteries that are common among adult population and associated with high incidence of morbidity and mortality. Using flow diverter stent alone to treat cerebral aneurysm is recognized as a safe and effective method. However, flow diverter stents currently available have limitations due to their braided structures. In this paper a novel flow diverter stent is proposed. It is made out of nitinol tubes that provide adequate radial stiffness and tailored surface coverage to overcome problems of currently available braided stents while retaining low porosity and excellent longitudinal flexibility. Finite element analysis using Abaqus has been conducted to investigate radial stiffness, longitudinal flexibility, and maximum strain during packaging of a series of novel stent designs with varied geometric parameters. Results show that porosity below 70% can be achieved and provides radial stiffness and longitudinal flexibility comparable to those of the Neuroform stent that is commonly used for stent assisted coiling. The novel flow diverter has showed great potential for direct treatment of cerebral aneurysms.
KeywordsCerebral aneurysm Flow diverter stent Finite element analysis Radial stiffness Longitudinal flexibility
The authors would like to thank Wellcome Trust and EPSRC for their financial support under Grant Number WT 088877/Z/09Z.
- 1.Abaqus. Version 6.7 Edition. Providence, RI: SIMULIA Corp.Google Scholar
- 3.Bederson, J. B., E. S. Connolly, H. H. Batjer, R. G. Dacey, J. E. Dion, M. N. Diringer, J. E. Duldner, R. E. Harbaugh, A. B. Patel, and R. H. Rosenwasser. Guidelines for the management of aneurysmal subarachnoid hemorrhage a statement for healthcare professionals from a special Writing Group of the Stroke Council, American Heart Association. Stroke 40(3):994–1025, 2009.PubMedCrossRefGoogle Scholar
- 6.Fiorella, D., F. C. Albuquerque, V. R. Deshmukh, H. H. Woo, P. A. Rasmussen, T. J. Masaryk, and C. G. McDougall. Endovascular reconstruction with the Neuroform stent as monotherapy for the treatment of uncoilable intradural pseudoaneurysms. Neurosurgery 59(2):291–300, 2006.PubMedCrossRefGoogle Scholar
- 10.Lylyk, P., C. Miranda, R. Ceratto, A. Ferrario, E. Scrivano, H. R. Luna, A. L. Berez, Q. Tran, P. K. Nelson, and D. Fiorella. Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: the Buenos Aires experience. Neurosurgery 64(4):632–643, 2009.PubMedCrossRefGoogle Scholar
- 13.Rebelo, N., X.-Y. Gong, A. Hall, A. R. Pelton, and T. W. Duerig. Finite element analysis on the cyclic properties of superelastic nitinol. In: Proceedings of the International Conference on Shape Memory and Superelastic Technologies, 2006, pp. 157–163.Google Scholar
- 14.Strother, C. M. Electrothrombosis of saccular aneurysms via endovascular approach: part 1 and part 2. AJNR Am. J. Neuroradiol. 22(5):1011–1012, 2001.Google Scholar
- 15.Szikora, I., Z. Berentei, Z. Kulcsar, M. Marosfoi, Z. Vajda, W. Lee, A. Berez, and P. Nelson. Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the pipeline embolization device. AJNR Am. J. Neuroradiol. 31(6):1139–1147, 2010.PubMedCrossRefGoogle Scholar