Annals of Biomedical Engineering

, Volume 34, Issue 8, pp 1259–1271 | Cite as

Computational Approach to Estimating the Effects of Blood Properties on Changes in Intra-stent Flow

Article
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Abstract

In this study various blood rheological assumptions are numerically investigated for the hemodynamic properties of intra-stent flow. Non-newtonian blood properties have never been implemented in blood coronary stented flow investigation, although its effects appear essential for a correct estimation and distribution of wall shear stress (WSS) exerted by the fluid on the internal vessel surface. Our numerical model is based on a full 3D stent mesh. Rigid wall and stationary inflow conditions are applied. Newtonian behavior, non-newtonian model based on Carreau-Yasuda relation and a characteristic newtonian value defined with flow representative parameters are introduced in this research. Non-newtonian flow generates an alteration of near wall viscosity norms compared to newtonian. Maximal WSS values are located in the center part of stent pattern structure and minimal values are focused on the proximal stent wire surface. A flow rate increase emphasizes fluid perturbations, and generates a WSS rise except for interstrut area. Nevertheless, a local quantitative analysis discloses an underestimation of WSS for modelisation using a newtonian blood flow, with clinical consequence of overestimate restenosis risk area. Characteristic viscosity introduction appears to present a useful option compared to rheological modelisation based on experimental data, with computer time gain and relevant results for quantitative and qualitative WSS determination.

Keywords

Non-newtonian Blood models Wall shear stress Computational fluid dynamics Characteristic viscosity 
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Notes

ACKNOWLEDGMENTS

The authors would like to thank the CINES, (Center Informatique Nationale de l’Education Supérieure, Montpellier, France) for making their IT resources and technical facilities available to us.

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Copyright information

© Biomedical Engineering Society 2006

Authors and Affiliations

  • Nicolas Benard
    • 1
  • Robert Perrault
    • 1
  • Damien Coisne
    • 1
    • 2
  1. 1.Laboratoire d’Etudes AérodynamiquesUniversité de PoitiersChasseneuil CedexFrance
  2. 2.Poitiers University HospitalPoitiersFrance

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