Annals of Biomedical Engineering

, Volume 34, Issue 6, pp 936–952 | Cite as

Fluid Dynamic Assessment of Three Polymeric Heart Valves Using Particle Image Velocimetry

  • Hwa Liang Leo
  • Lakshmi Prasad Dasi
  • Josie Carberry
  • Hélène A. Simon
  • Ajit P. Yoganathan

Polymeric heart valves have the potential to reduce thrombogenic complications associated with current mechanical valves and overcome fatigue-related problems experienced by bioprosthetic valves. In this paper we characterize the in vitro velocity and Reynolds Shear Stress (RSS) fields inside and downstream of three different prototype trileaflet polymeric heart valves. The fluid dynamic differences are then correlated with variations in valve design parameters. The three valves differ in leaflet thickness, ranging from 80 to 120 μm, and commisural design, either closed, opened, or semi-opened. The valves were subjected to aortic flow conditions and the velocity measured using three-dimensional stereo Particle Image Velocimetry. The peak forward flow phase in the three valves was characterized by a strong central orifice jet of approximately 2 m/s with a flat profile along the trailing edge of the leaflets. Leakage jets, with principle RSS magnitudes exceeding 4,500 dyn/cm2, were observed in all valves with larger leaflet thicknesses and also corresponded to larger leakage volumes. Additional leakage jets were observed at the commissural region of valves with the open and the semi-open commissural designs. The results of the present study indicate that commissural design and leaflet thickness influence valve fluid dynamics and thus the thrombogenic potential of trileaflet polymeric valves.


Heart valve PIV Particle Image Velocimetry Thrombogenic Polyurethanes Coaptation Washout Trileaflet valve Polymer 



This work was partially supported by a grant from the National Heart, Lung and Blood Institute (HL 720621). The authors wish to thank Aortech, Inc for providing the prototype valves.


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Hwa Liang Leo
    • 1
    • 2
  • Lakshmi Prasad Dasi
    • 1
  • Josie Carberry
    • 1
  • Hélène A. Simon
    • 3
  • Ajit P. Yoganathan
    • 1
    • 4
  1. 1.Wallace H. Coulter School of Biomedical EngineeringGeorgia Institute of TechnologyAtlantaUSA
  2. 2.Woodruff School of Mechanical EngineeringGeorgia Institute of TechnologyAtlantaUSA
  3. 3.School of Chemical and Biomolecular EngineeringGeorgia Institute of TechnologyAtlantaUSA
  4. 4.Wallace H. Coulter School of Biomedical EngineeringGeorgia Institute of TechnologyAtlantaUSA

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