Effect of local longitudinal shortening on the transport of luminal contents through small intestine
- 30 Downloads
A theoretical analysis of the rheological fluid flow due to peristalsis is studied. We have applied the classical lubrication theory to predict the near physiological behavior of the intestinal segment, mixing and transport. A parametric study involving the changes in local longitudinal shortening (LLS) magnitude, LLS spacing, fluid viscosity, wavelength of the wave, and occlusion of lumen caused by the wave provided insights into the dynamics of the peristalsis flow of a non-Newtonian fluid. LLS appear to have little significance in modulating the flow patterns that are caused by circular contraction alone. Results also indicate that there exists trade-off between the power requirement for peristalsis at a certain occlusion against the percentage LLS. LLS appear to be more advantageous to perform the peristalsis activity at higher occlusion than lower occlusion. Having mucosal folds in the inner lining of the intestine allows for one more advantage of slowing the transit due to increased friction factor and increase in time for absorption of the nutrients.
KeywordsCircular contraction Local longitudinal shortening Lubrication theory
- 6.Sugarbaker, D.J., Rattan, S., Goyal, R.K.: Mechanical and electrical activity of esophageal smooth muscle during peristalsis. Am. J. Physiol. 246, G145–150 (1984)Google Scholar
- 7.Sugarbaker, D.J., Rattan, S., Goyal, R.K.: Swallowing induces sequential activation of esophageal longitudinal smooth muscle. Am. J. Physiol. 247, G515–519 (1984)Google Scholar
- 12.Latham, T.W.: Fluid Motion in a Peristaltic Pump. Massachusetts Institute of Technology, Cambridge (1966)Google Scholar
- 22.Ravi Kant, A.: Bio-mechanics of the distal stomach and duodenum: an insight into mechanisms of duodenogastric reflux and duodenal mixing. in: 48th Graduating Students Convocation 2015, Indian Institute of Technology, Kanpur, June 07, 2015.Google Scholar