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Characterization of glass frit capillary pumps for microfluidic devices

  • Matthew Rich
  • Omar Mohd
  • Frances S. Ligler
  • Glenn M. WalkerEmail author
Short Communication
  • 51 Downloads

Abstract

Here, we report on a low-cost, disposable microfluidic pump made from sieved glass particles. The pump overcomes the limitations of other passive pumping methods and can handle whole blood, which makes it useful for point-of-care diagnostics. Flow rates of up to 8.7 µL/s and pumping volumes of up to 1 mL were demonstrated, but both can be adjusted by changing pump geometry and particle size. Finally, we demonstrate utility of this pump by attaching it to a commercially available point-of-care immunoassay system from mBio Diagnostics and demonstrating improved binding efficiencies with flow.

Keywords

Porous Glass Capillary forces Pump Microfluidic Point-of-care 

Notes

Acknowledgements

This work was supported by the North Carolina State University Chancellors Innovation Fund, the North Carolina Biotechnology Center Technology Enhancement Grant, and the Ross Lampe Chair in Biomedical Engineering at North Carolina State University.

Supplementary material

10404_2019_2238_MOESM1_ESM.docx (135 kb)
Supplementary material 1 (DOCX 135 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Joint Department of Biomedical EngineeringUniversity of North Carolina at Chapel Hill and North Carolina State UniversityRaleighUSA
  2. 2.Department of Electrical EngineeringUniversity of MississippiOxfordUSA

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