Characterization of glass frit capillary pumps for microfluidic devices
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Here, we report on a low-cost, disposable microfluidic pump made from sieved glass particles. The pump overcomes the limitations of other passive pumping methods and can handle whole blood, which makes it useful for point-of-care diagnostics. Flow rates of up to 8.7 µL/s and pumping volumes of up to 1 mL were demonstrated, but both can be adjusted by changing pump geometry and particle size. Finally, we demonstrate utility of this pump by attaching it to a commercially available point-of-care immunoassay system from mBio Diagnostics and demonstrating improved binding efficiencies with flow.
KeywordsPorous Glass Capillary forces Pump Microfluidic Point-of-care
This work was supported by the North Carolina State University Chancellors Innovation Fund, the North Carolina Biotechnology Center Technology Enhancement Grant, and the Ross Lampe Chair in Biomedical Engineering at North Carolina State University.
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