Microfluidics and Nanofluidics

, Volume 13, Issue 4, pp 683–694

Ferrofluid actuation with varying magnetic fields for micropumping applications

  • Evrim Kurtoğlu
  • Alp Bilgin
  • Muhsincan Şeşen
  • Burç Mısırlıoğlu
  • Mehmet Yıldız
  • Havva Funda Yağcı Acar
  • Ali Koşar
Research Paper

Abstract

Magnetic nanoparticle suspensions and their manipulation are becoming an alternative research line. They have vital applications in the field of microfluidics such as microscale flow control in microfluidic circuits, actuation of fluids in microscale, and drug delivery mechanisms. In microscale, it is possible and beneficial to use magnetic fields as actuators of such ferrofluids, where these fluids could move along a dynamic gradient of magnetic field so that a micropump could be generated with this technique. Thus, magnetically actuated ferrofluids could have the potential to be used as an alternative micro pumping system. Magnetic actuation of nanofluids is becoming an emergent field that will open up new possibilities in various fields of engineering. Different families of devices actuating ferrofluids were designed and developed in this study to reveal this potential. A family of these devices actuates discrete plugs, whereas a second family of devices generates continuous flows in tubes of inner diameters ranging from 254 μm to 1.56 mm. The devices were first tested with minitubes to prove the effectiveness of the proposed actuation method. The setups were then adjusted to conduct experiments on microtubes. Promising results were obtained from the experiments. Flow rates up to 120 and 0.135 μl/s were achieved in minitubes and microtubes with modest maximum magnetic field magnitudes of 300 mT for discontinuous and continuous actuation, respectively. The proposed magnetic actuation method was proven to work as intended and is expected to be a strong alternative to the existing micropumping methods such as electromechanical, electrokinetic, and piezoelectric actuation. The results suggest that ferrofluids with magnetic nanoparticles merit more research efforts in micro pumping.

Keywords

Microfluidics Microchannel Magnetic actuation Ferrofluids Nanofluids Pumps Magnetohydrodynamics 

References

  1. Acar HY, Garaas RS, Syud F, Bonitatebus P, Kulkarni AM (2005) Superparamagnetic nanoparticles stabilized by polymerized PEGylated coatings. J Magn Magn Mater 293:1–7CrossRefGoogle Scholar
  2. Afshar R, Lehnert T, Moser Y, Gijs MAM (2009) Magnetic particle dosing, release and separation in a microfluidic chip with magnetic actuation. In: International Solid-State Sensors, Actuators and Microsystems Conference, 2009. TRANSDUCERS 2009, Denver, CO, USAGoogle Scholar
  3. Al-Halhouli AT, Kilani MI, Büttgenbach S (2010) Development of a novel electromagnetic pump for biomedical applications. Sens Actuators A 162:172–176CrossRefGoogle Scholar
  4. Ando B, Baglio S, Beninato A (2009) Non-invasive implementation of pumping mechanism in pre-existing capillary. In: IEEE Sensors 2009 ConferenceGoogle Scholar
  5. Ando B, Salvatore B, Beninato A (2011) An IR methodology to assess the behavior of ferrofluidic transducers case of study: a contactless driven pump. IEEE Sens J 11:1CrossRefGoogle Scholar
  6. Anton I, Vekas L, Potencz I, Suciu E (1980) Ferrofluid flow under the influence of rotating magnetic fields. IEEE Trans Magn 16:283–287CrossRefGoogle Scholar
  7. Bilgin A, Kurtoglu E, Erk HC, Yagci-Acar HF, Koşar A. (2011a) A novel magnetomechanical pump to actuate ferrofluids in microchannels. In: Thermal and materials nanoscience and nanotechnology 2011, TMNN2011, May 29–June 03, Antalya, TurkeyGoogle Scholar
  8. Bilgin A, Kurtoglu E, Erk HC, Yagci- Acar HF, Kubilay A, Koşar A (2011b) Magnetic nanoparticle based nanofluid actuation with dynamic magnetic fields. In: Proceedings of the ASME 2011 9th international conference on nanochannels, microchannels, and minichannels, ICNMM 9, June 19–22, Edmonton, Canada, ICNMM2011-58222Google Scholar
  9. Chen H, Abolmatty A, Faghri M (2011a) Microfluidic inverse phase ELISA via manipulation of magnetic beads. Microfluid Nanofluid 10:593–605CrossRefGoogle Scholar
  10. Chen YA, Huang ZW, Tsai FS, Chen CY, Lin CM, Wo AM (2011b) Analysis of sperm concentration and motility in a microfluidic device. Microfluid Nanofluid 10:59–67CrossRefGoogle Scholar
  11. Choi HS, Kim YS, Kim KT, Park IH (2008) Simulation of hydrostatical equillibrium of ferrofluid subject to magneto-static field. IEEE Trans Magn 44:818–821CrossRefGoogle Scholar
  12. Dababneh MS, Ayoub NY (1995) The effect of Oleic Acid on the stability of magnetic ferrofluid. IEEE Trans on Magn 31:4178–4180CrossRefGoogle Scholar
  13. Derec C, Wilhelm C, Servais J, Bacri JC (2010) Local control of magnetic objects in microfluidic channels. Microfluidics Nanofluidics 8:123–130CrossRefGoogle Scholar
  14. Greivell NE, Hannaford B (1997) The design of a ferrofluid magnetic pipette. IEEE Trans Biomed Eng 44(3):129–135CrossRefGoogle Scholar
  15. GUM (Guide to the Expression of Uncertainty in Measurement)-ISO, 1995. (with minor corrections), Evaluation of measurement data—Guide to the expression of uncertainty in measurement. Joint Committee for Guides in Metrology (JCGM), 100:2008Google Scholar
  16. Hartshorne H, Backhouse CJ, Lee WE (2004) Ferrofluid-based microchip pump and valve. Sens Actuators B 99:592–600CrossRefGoogle Scholar
  17. Hatch A, Kamholz AE, Holman G, Yager P, Böhringer FK (2001) A ferrofluidic magnetic micropump. J Microelectromech Syst 10(2):1CrossRefGoogle Scholar
  18. Jin X, Aluru NR (2011) Gated transport in nanofluidic devices. Microfluid Nanofluid. doi:10.1007/s10404-011-0796-3 Google Scholar
  19. Kakaç S, Pramuanjaroenkij A (2009) Review of convective heat transfer enhancements with nanofluids. Int J Heat Mass Transf 52:3187–3196MATHCrossRefGoogle Scholar
  20. Karle M, Wöhrle J, Miwa J, Paust N, Roth G, Zengerle R, Stetten F (2010) Controlled counter-flow motion of magnetic bead chains rolling along microchannels. Microfluid Nanofluid 10:935–939CrossRefGoogle Scholar
  21. Kline S, McClintock FA (1953) Describing Uncertainties in Single-Sample Experiments. Mech Eng (Am Soc Mech Eng) 75:3–8Google Scholar
  22. Kong TF, Shin H, Sugiarto HS, Liew HF, Wang X, Lew WS, Nguyen NT, Chen Y (2011) An efficient microfluidic sorter: implementation of double meandering micro striplines for magnetic particles switching. Microfluid Nanofluid 10:1069–1078CrossRefGoogle Scholar
  23. Kurtoglu, E, Bilgin, A, Erk, HC, Yagci-Acar, HF, Sesen, M, Koşar, A (2011) Implementation of a simplified method for actuation of ferrofluids. In: Third micro and nanoflows conference, Paper no: 26, MNF 2011, August 22–24, Thessaloniki, GreeceGoogle Scholar
  24. Lacharme F, Vandevyer C, Gijs MAM (2009) Magnetic beads retention device for sandwich immunoassay: comparison of off-chip and on-chip antibody incubation. Microfluid Nanofluid 7:497CrossRefGoogle Scholar
  25. Leland, JE (1991) Ferrofluid piston pump for use with heat pipes or the like. U.S. patent 5 005 639Google Scholar
  26. Lien KY, Liu CJ, Lin YC, Kuo PL, Lee GB (2009) Extraction of genomic DNA and detection of single nucleotide polymorphism genotyping utilizing an integrated magnetic bead-based microfluidic platform. Microfluid Nanofluid 6:539–555CrossRefGoogle Scholar
  27. Love LJ, Jansen JF, McKnight TE, Roh Y, Phelps TJ, Yeary LW, Cunningham GT (2005) Ferrofluid field induced flow for microfluidic applications. IEEE/ASME Trans Mechatron 10:68–76CrossRefGoogle Scholar
  28. Mao L, Koser H (2011) An integrated MEMS ferrofluid pump using insulated metal substrate. In: 31st Annual conference of IEE, IECON 2005, pp 2372–2375Google Scholar
  29. Martsenyuk MA (1980) A dissipative process in ferrofluid in non-homogenous magnetic field. IEEE Trans Magn 16:298–300CrossRefGoogle Scholar
  30. Menz A, Benecke W, Perez-Castillejos R, Plaza JA, Esteve J, Garcia N, Higuero J, Diez-Caballiero T (2000) Fluidic components based on ferrofluids. In: Proceedings from 1st annual international IEEE-EMBS special topic conference on microtechnologies in medicine and biology, Lyon, FranceGoogle Scholar
  31. Pamme N (2006) Magnetism and microfluidics. Lab Chip 6:24–38CrossRefGoogle Scholar
  32. Pérez-Castillejos R, Plaza JA, Esteve J, Losantos P, Acero MC, Cane C, Serra-Mestres F (2000) The use of ferrofluids in micromechanics. Sens Actuators A 84:176–180CrossRefGoogle Scholar
  33. Sanders GHW, Manz A (2000) Chip- based microsystems for genomic and proteomic analysis. Trends in Analytical Chemistry 19(6):364–378CrossRefGoogle Scholar
  34. Sing CE, Schmid L, Schneider MF, Franke T, Alexander-Katz A (2010) Controlled surface-induced flows from the motion of self-assembled colloidal walkers. PNAS 107:535–540CrossRefGoogle Scholar
  35. Song W, Ding Z, Son C, Ziaie B (2007) A dynamic ferrofluid platform for micromanipulation, MEMS 2007. Kobe, JapanGoogle Scholar
  36. Tierno P, Golestanian R, Pagonabarraga I, Sagues F (2008) Controlled swimming in confined fluids of magnetically actuated colloidal rotors. Phys Rev Lett 101:21830–21834CrossRefGoogle Scholar
  37. Tsai KL, Pickard D, Kao J, Yin X, Leen B, Knutson K, Kant R, Howe RT (2009) Magnetic nanoparticle-driven pumping in microchannels. In: Transducers 2009, Denver, CO, USAGoogle Scholar
  38. Van Lintel HTG, Van de Pol FCM, Bouwstra S (1988) A piezoelectric micropump based on micromachining of silicon. Sens Actuators 15:153–167CrossRefGoogle Scholar
  39. Veeramachaneni UK, Carroll RL (2007). Excerpt from the Proceedings of the COMSOL Conference. Boston, MAGoogle Scholar
  40. Wang Y, Zhao Y, Cho SK (2007) In-droplet magnetic beads concentration and seperation for digital microfluidics. In: The 14th international conference on solid-state sensors, actuators and microsystems, Transducers and Eurosensors’07, Lyon, FranceGoogle Scholar
  41. Woias P (2004) Micropumps-past, progress and future prospects. Sens Actators B 105:28–38Google Scholar
  42. Yamahata C, Chastellain M, Parashar VK, Petri A, Hofmann H, Gijs MAM (2005) Plastic micropump with ferrofluidic actuation. J Microelectromech Syst 14(1):96–102CrossRefGoogle Scholar
  43. Zhang R, Dalton C, Jullien GA (2011) Two-phase AC electrothermal fluidic pumping in a coplanar asymmetric electrode array. Microfluid Nanofluid 10:521–529CrossRefGoogle Scholar
  44. Zhu T, Cheng R, Mao L (2011) Focusing microparticles in a microfluidic channel with ferrofluids. Microfluid Nanofluid. doi:10.1007/s10404-011-0835-0 Google Scholar

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Evrim Kurtoğlu
    • 1
  • Alp Bilgin
    • 1
  • Muhsincan Şeşen
    • 1
  • Burç Mısırlıoğlu
    • 2
  • Mehmet Yıldız
    • 2
  • Havva Funda Yağcı Acar
    • 3
  • Ali Koşar
    • 1
  1. 1.Mechatronics Engineering ProgramSabanci UniversityIstanbulTurkey
  2. 2.Material Science Engineering ProgramSabanci UniversityIstanbulTurkey
  3. 3.Department of ChemistryKoc UniversityIstanbulTurkey

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